KCNB2-AS1

Summary

KCNB2-AS1 (KCNB2 antisense RNA 1, HGNC:58256) is a long non-coding RNA gene on chromosome 8q21.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58256
Approved symbol	KCNB2-AS1
Name	KCNB2 antisense RNA 1
Location	8q21.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253784
Ensembl biotype	lncRNA
Entrez	139355243
RNAcentral	URS000025064B — lncRNA, 488 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000523881

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000523881 — 3 exons

Exon	Start	End
ENSE00002103967	72881495	72881595
ENSE00002118654	72881699	72881740
ENSE00002123371	72874859	72875203

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 77.76.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	77.76	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.00	gold quality
cortical plate	UBERON:0005343	65.38	gold quality
urinary bladder	UBERON:0001255	60.38	silver quality
kidney	UBERON:0002113	58.37	silver quality
islet of Langerhans	UBERON:0000006	56.60	gold quality
bone marrow	UBERON:0002371	56.54	gold quality
prefrontal cortex	UBERON:0000451	55.53	gold quality
blood	UBERON:0000178	54.68	gold quality
adrenal tissue	UBERON:0018303	53.60	gold quality
left coronary artery	UBERON:0001626	52.92	gold quality
monocyte	CL:0000576	50.13	silver quality
corpus callosum	UBERON:0002336	47.75	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.38	gold quality
gastrocnemius	UBERON:0001388	47.25	silver quality
body of pancreas	UBERON:0001150	47.06	gold quality
frontal cortex	UBERON:0001870	46.97	gold quality
esophagus mucosa	UBERON:0002469	46.14	gold quality
tibial nerve	UBERON:0001323	46.03	silver quality
tibial artery	UBERON:0007610	45.74	gold quality
esophagus	UBERON:0001043	45.69	gold quality
heart	UBERON:0000948	45.60	gold quality
temporal lobe	UBERON:0001871	45.50	gold quality
cerebral cortex	UBERON:0000956	45.21	gold quality
cerebellar hemisphere	UBERON:0002245	44.64	silver quality
lung	UBERON:0002048	44.41	gold quality
right lobe of liver	UBERON:0001114	44.08	silver quality
stomach	UBERON:0000945	43.19	gold quality
brain	UBERON:0000955	42.89	gold quality
heart left ventricle	UBERON:0002084	42.74	silver quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-CURD-119	no	1163.85
E-GEOD-131882	no	414.09
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.