KCNH1-IT1

Summary

KCNH1-IT1 (KCNH1 intronic transcript 1, HGNC:41351) is a long non-coding RNA gene on chromosome 1q32.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41351
Approved symbol	KCNH1-IT1
Name	KCNH1 intronic transcript 1
Location	1q32.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234233
Ensembl biotype	lncRNA
Entrez	100874296
RNAcentral	URS0000BC4558 — lncRNA, 935 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000438597

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438597 — 2 exons

Exon	Start	End
ENSE00004097572	211132580	211133026
ENSE00004097573	211133188	211133470

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 88.29.

Top tissues by expression

104 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.29	gold quality
right hemisphere of cerebellum	UBERON:0014890	73.47	gold quality
cerebellar hemisphere	UBERON:0002245	72.82	gold quality
cerebellar cortex	UBERON:0002129	72.73	gold quality
cerebellum	UBERON:0002037	72.62	gold quality
right frontal lobe	UBERON:0002810	68.82	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.44	gold quality
frontal cortex	UBERON:0001870	67.92	gold quality
prefrontal cortex	UBERON:0000451	67.40	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.32	gold quality
cerebral cortex	UBERON:0000956	66.91	gold quality
superior frontal gyrus	UBERON:0002661	66.18	gold quality
skeletal muscle tissue	UBERON:0001134	66.10	silver quality
anterior cingulate cortex	UBERON:0009835	65.62	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	64.94	gold quality
primary visual cortex	UBERON:0002436	64.85	gold quality
brain	UBERON:0000955	64.42	gold quality
islet of Langerhans	UBERON:0000006	64.23	gold quality
ventricular zone	UBERON:0003053	63.99	gold quality
corpus callosum	UBERON:0002336	63.84	gold quality
putamen	UBERON:0001874	63.23	gold quality
Ammon’s horn	UBERON:0001954	62.71	gold quality
ganglionic eminence	UBERON:0004023	62.20	gold quality
substantia nigra	UBERON:0002038	61.50	gold quality
temporal lobe	UBERON:0001871	61.49	gold quality
nucleus accumbens	UBERON:0001882	61.45	gold quality
amygdala	UBERON:0001876	61.44	gold quality
caudate nucleus	UBERON:0001873	60.27	gold quality
duodenum	UBERON:0002114	59.15	gold quality
stromal cell of endometrium	CL:0002255	58.07	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.