KCNH7-AS1

Summary

KCNH7-AS1 (KCNH7 antisense RNA 1, HGNC:40858) is a long non-coding RNA gene on chromosome 2q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40858
Approved symbol	KCNH7-AS1
Name	KCNH7 antisense RNA 1
Location	2q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237750
Ensembl biotype	lncRNA
Entrez	101929570
RNAcentral	URS00007E4409 — lncRNA, 3016 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000446838, ENST00000780946, ENST00000780947

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446838 — 5 exons

Exon	Start	End
ENSE00001675283	162795396	162797972
ENSE00001694988	162784597	162784736
ENSE00001743131	162768936	162768988
ENSE00001754616	162771931	162771991
ENSE00001766358	162784993	162785160

Expression profiles

Bgee: expression breadth broad, 17 present calls, max score 88.26.

Top tissues by expression

169 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	88.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.63	gold quality
buccal mucosa cell	CL:0002336	71.23	silver quality
right testis	UBERON:0004534	56.04	gold quality
testis	UBERON:0000473	55.75	gold quality
adrenal tissue	UBERON:0018303	55.55	gold quality
left testis	UBERON:0004533	55.13	gold quality
tibialis anterior	UBERON:0001385	55.03	silver quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
epithelial cell of pancreas	CL:0000083	53.91	gold quality
pancreatic ductal cell	CL:0002079	53.89	silver quality
ileal mucosa	UBERON:0000331	53.64	silver quality
upper arm skin	UBERON:0004263	53.52	gold quality
cardiac atrium	UBERON:0002081	51.83	gold quality
uterine cervix	UBERON:0000002	51.44	silver quality
deltoid	UBERON:0001476	51.35	gold quality
gastrocnemius	UBERON:0001388	50.34	silver quality
myocardium	UBERON:0002349	50.25	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality
upper lobe of lung	UBERON:0008948	46.85	silver quality
quadriceps femoris	UBERON:0001377	46.58	gold quality
heart	UBERON:0000948	46.38	gold quality
metanephros	UBERON:0000081	46.07	gold quality
vastus lateralis	UBERON:0001379	45.40	gold quality
skeletal muscle tissue	UBERON:0001134	45.19	gold quality
adult mammalian kidney	UBERON:0000082	44.98	gold quality
corpus callosum	UBERON:0002336	44.09	silver quality
heart left ventricle	UBERON:0002084	43.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.61

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.