KCNIP1-OT1

Summary

KCNIP1-OT1 (KCNIP1 overlapping transcript 1, HGNC:40320) is a long non-coding RNA gene on chromosome 5q35.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40320
Approved symbol	KCNIP1-OT1
Name	KCNIP1 overlapping transcript 1
Location	5q35.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000253647
Ensembl biotype	lncRNA
Entrez	101928033
RNAcentral	URS00001F03BC — lncRNA, 1215 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000518387

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000518387 — 3 exons

Exon	Start	End
ENSE00002090550	170421971	170422844
ENSE00004213350	170389490	170389603
ENSE00004213351	170420386	170420615

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 79.75.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0785 / max 14.5034, expressed in 34 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
60152	0.0785	34

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.75	gold quality
smooth muscle tissue	UBERON:0001135	64.10	gold quality
myometrium	UBERON:0001296	63.04	gold quality
body of uterus	UBERON:0009853	62.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	61.55	gold quality
popliteal artery	UBERON:0002250	61.34	gold quality
tibial artery	UBERON:0007610	61.33	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	61.22	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.46	gold quality
cortical plate	UBERON:0005343	60.44	gold quality
lower esophagus	UBERON:0013473	60.39	gold quality
monocyte	CL:0000576	59.97	gold quality
tonsil	UBERON:0002372	59.31	silver quality
ventricular zone	UBERON:0003053	59.22	silver quality
right coronary artery	UBERON:0001625	58.76	gold quality
calcaneal tendon	UBERON:0003701	58.33	gold quality
descending thoracic aorta	UBERON:0002345	57.50	gold quality
urinary bladder	UBERON:0001255	56.65	gold quality
colon	UBERON:0001155	56.28	gold quality
hindlimb stylopod muscle	UBERON:0004252	55.64	silver quality
esophagus	UBERON:0001043	55.39	gold quality
bone marrow	UBERON:0002371	55.20	silver quality
thoracic aorta	UBERON:0001515	55.01	gold quality
ascending aorta	UBERON:0001496	54.67	gold quality
intestine	UBERON:0000160	54.65	gold quality
ectocervix	UBERON:0012249	54.06	gold quality
left coronary artery	UBERON:0001626	53.83	gold quality
apex of heart	UBERON:0002098	53.76	gold quality
duodenum	UBERON:0002114	53.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.