KCNJ2-AS1

Summary

KCNJ2-AS1 (KCNJ2 antisense RNA 1, HGNC:43720) is a long non-coding RNA gene on chromosome 17q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43720
Approved symbol	KCNJ2-AS1
Name	KCNJ2 antisense RNA 1
Location	17q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ36644
Ensembl gene	ENSG00000267365
Ensembl biotype	lncRNA
Entrez	400617
RNAcentral	URS00001E66EF — lncRNA, 2442 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000590966

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000590966 — 1 exons

Exon	Start	End
ENSE00003986181	70166961	70169404

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 89.85.

FANTOM5 (CAGE): breadth broad, TPM avg 1.4084 / max 89.1830, expressed in 559 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
167814	0.8945	448
167813	0.3777	143
167812	0.1362	43

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.85	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.57	gold quality
gastrocnemius	UBERON:0001388	75.01	gold quality
muscle of leg	UBERON:0001383	74.60	gold quality
bone marrow cell	CL:0002092	73.99	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.25	gold quality
spinal cord	UBERON:0002240	70.22	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.99	gold quality
right uterine tube	UBERON:0001302	68.75	gold quality
apex of heart	UBERON:0002098	68.09	gold quality
heart left ventricle	UBERON:0002084	67.59	gold quality
cardiac ventricle	UBERON:0002082	66.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.52	gold quality
monocyte	CL:0000576	65.63	gold quality
leukocyte	CL:0000738	65.34	gold quality
rectum	UBERON:0001052	63.62	gold quality
prefrontal cortex	UBERON:0000451	63.22	gold quality
heart	UBERON:0000948	62.59	gold quality
islet of Langerhans	UBERON:0000006	62.46	gold quality
putamen	UBERON:0001874	62.37	gold quality
amygdala	UBERON:0001876	61.94	gold quality
nucleus accumbens	UBERON:0001882	61.64	gold quality
right atrium auricular region	UBERON:0006631	61.59	gold quality
vermiform appendix	UBERON:0001154	61.48	gold quality
blood	UBERON:0000178	61.17	gold quality
cardiac atrium	UBERON:0002081	61.04	gold quality
ventricular zone	UBERON:0003053	60.87	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.85	gold quality
lower esophagus	UBERON:0013473	60.83	gold quality
substantia nigra	UBERON:0002038	60.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.