KCNJ5-AS1

Summary

KCNJ5-AS1 (KCNJ5 antisense RNA 1, HGNC:28584) is a long non-coding RNA gene on chromosome 11q24.3.

Predicted to be located in extracellular region.

Source: NCBI Gene 219833 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28584
Approved symbol	KCNJ5-AS1
Name	KCNJ5 antisense RNA 1
Location	11q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC35558, FLJ43646
Ensembl gene	ENSG00000174370
Ensembl biotype	lncRNA
Entrez	219833
RNAcentral	URS0001BBE59D — lncRNA, 3582 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000310799, ENST00000524878, ENST00000730925, ENST00000730926, ENST00000730927

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000310799 — 4 exons

Exon	Start	End
ENSE00001197115	128903367	128903511
ENSE00001197119	128905549	128905697
ENSE00001197125	128899565	128902713
ENSE00003900922	128904431	128904611

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 73.65.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 2.2779 / max 242.5244, expressed in 128 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
123117	2.2779	128

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right adrenal gland cortex	UBERON:0035827	73.65	gold quality
right adrenal gland	UBERON:0001233	73.59	gold quality
apex of heart	UBERON:0002098	73.31	gold quality
left adrenal gland	UBERON:0001234	72.46	gold quality
left adrenal gland cortex	UBERON:0035825	72.40	gold quality
adrenal cortex	UBERON:0001235	70.41	gold quality
heart left ventricle	UBERON:0002084	70.28	gold quality
adrenal gland	UBERON:0002369	69.67	gold quality
cardiac ventricle	UBERON:0002082	69.56	gold quality
esophagus squamous epithelium	UBERON:0006920	68.24	gold quality
body of pancreas	UBERON:0001150	68.09	gold quality
right atrium auricular region	UBERON:0006631	67.99	gold quality
amniotic fluid	UBERON:0000173	67.74	silver quality
descending thoracic aorta	UBERON:0002345	67.41	gold quality
cardiac atrium	UBERON:0002081	67.29	gold quality
heart	UBERON:0000948	66.82	gold quality
skin of hip	UBERON:0001554	66.16	gold quality
gall bladder	UBERON:0002110	65.76	gold quality
secondary oocyte	CL:0000655	65.25	gold quality
adrenal tissue	UBERON:0018303	65.13	gold quality
thoracic aorta	UBERON:0001515	64.92	gold quality
pituitary gland	UBERON:0000007	64.79	gold quality
right coronary artery	UBERON:0001625	64.77	gold quality
esophagus mucosa	UBERON:0002469	64.67	gold quality
ascending aorta	UBERON:0001496	64.58	gold quality
nucleus accumbens	UBERON:0001882	64.25	gold quality
pancreas	UBERON:0001264	64.15	gold quality
adenohypophysis	UBERON:0002196	63.57	gold quality
lower esophagus mucosa	UBERON:0035834	63.34	gold quality
skin of abdomen	UBERON:0001416	63.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.92

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.