KCNJ8-AS1

Summary

KCNJ8-AS1 (KCNJ8 antisense RNA 1, HGNC:58193) is a long non-coding RNA gene on chromosome 12p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58193
Approved symbol	KCNJ8-AS1
Name	KCNJ8 antisense RNA 1
Location	12p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256615
Ensembl biotype	lncRNA
Entrez	105369689
RNAcentral	URS0002A21685 — lncRNA, 1244 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000716337, ENST00000716338, ENST00000716339

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000716337 — 3 exons

Exon	Start	End
ENSE00002203369	21662313	21662771
ENSE00002263615	21759914	21760085
ENSE00004029520	21766356	21766968

Expression profiles

Bgee: expression breadth broad, 83 present calls, max score 89.14.

Top tissues by expression

83 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.14	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.84	gold quality
small intestine	UBERON:0002108	69.97	silver quality
right lung	UBERON:0002167	64.08	gold quality
ganglionic eminence	UBERON:0004023	62.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.19	gold quality
monocyte	CL:0000576	59.64	gold quality
placenta	UBERON:0001987	58.05	gold quality
lung	UBERON:0002048	54.55	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.04	gold quality
islet of Langerhans	UBERON:0000006	53.03	gold quality
upper lobe of left lung	UBERON:0008952	52.17	gold quality
calcaneal tendon	UBERON:0003701	52.13	silver quality
smooth muscle tissue	UBERON:0001135	51.04	gold quality
adrenal tissue	UBERON:0018303	51.03	gold quality
kidney	UBERON:0002113	50.90	gold quality
endometrium	UBERON:0001295	50.85	gold quality
adult mammalian kidney	UBERON:0000082	50.22	gold quality
prefrontal cortex	UBERON:0000451	50.11	gold quality
superior frontal gyrus	UBERON:0002661	49.77	gold quality
blood	UBERON:0000178	49.39	silver quality
liver	UBERON:0002107	49.33	silver quality
lymph node	UBERON:0000029	48.37	silver quality
right lobe of thyroid gland	UBERON:0001119	48.25	gold quality
muscle of leg	UBERON:0001383	47.93	gold quality
testis	UBERON:0000473	47.73	gold quality
right lobe of liver	UBERON:0001114	47.08	silver quality
gastrocnemius	UBERON:0001388	46.54	silver quality
multicellular organism	UBERON:0000468	46.38	gold quality
right testis	UBERON:0004534	45.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.