KCNK10-AS1

Summary

KCNK10-AS1 (KCNK10 antisense RNA 1, HGNC:58074) is a long non-coding RNA gene on chromosome 14q31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58074
Approved symbol	KCNK10-AS1
Name	KCNK10 antisense RNA 1
Location	14q31.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	AL133279.1
Ensembl gene	ENSG00000258538
Ensembl biotype	lncRNA
Entrez	105370612
RNAcentral	URS0002A578E3 — lncRNA, 557 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000553487, ENST00000556789, ENST00000828378

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553487 — 3 exons

Exon	Start	End
ENSE00002490766	88179898	88180198
ENSE00002497094	88177072	88177152
ENSE00002503081	88175391	88175481

Expression profiles

Bgee: expression breadth broad, 62 present calls, max score 88.44.

Top tissues by expression

62 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.44	gold quality
left testis	UBERON:0004533	74.81	gold quality
right testis	UBERON:0004534	74.01	gold quality
testis	UBERON:0000473	73.82	gold quality
prefrontal cortex	UBERON:0000451	57.81	gold quality
liver	UBERON:0002107	57.66	gold quality
multicellular organism	UBERON:0000468	56.67	gold quality
islet of Langerhans	UBERON:0000006	56.25	gold quality
monocyte	CL:0000576	56.24	silver quality
right lobe of liver	UBERON:0001114	55.05	gold quality
blood	UBERON:0000178	54.62	gold quality
gastrocnemius	UBERON:0001388	53.13	gold quality
left coronary artery	UBERON:0001626	49.29	gold quality
body of pancreas	UBERON:0001150	49.09	gold quality
tibial artery	UBERON:0007610	48.21	gold quality
skin of leg	UBERON:0001511	48.02	gold quality
heart left ventricle	UBERON:0002084	47.77	gold quality
thoracic aorta	UBERON:0001515	47.75	gold quality
ascending aorta	UBERON:0001496	47.41	gold quality
heart	UBERON:0000948	47.32	gold quality
urinary bladder	UBERON:0001255	46.76	gold quality
tonsil	UBERON:0002372	46.67	gold quality
tibial nerve	UBERON:0001323	46.62	gold quality
transverse colon	UBERON:0001157	45.21	gold quality
cerebellar cortex	UBERON:0002129	44.72	silver quality
Ammon’s horn	UBERON:0001954	44.55	gold quality
body of stomach	UBERON:0001161	44.42	gold quality
stomach	UBERON:0000945	44.34	silver quality
subcutaneous adipose tissue	UBERON:0002190	44.05	gold quality
esophagus mucosa	UBERON:0002469	43.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.47

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.