KCNMA1-AS2

Summary

KCNMA1-AS2 (KCNMA1 antisense RNA 2, HGNC:51214) is a long non-coding RNA gene on chromosome 10q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51214
Approved symbol	KCNMA1-AS2
Name	KCNMA1 antisense RNA 2
Location	10q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225497
Ensembl biotype	lncRNA
Entrez	101929310
RNAcentral	URS000075A948 — lncRNA, 445 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000428936, ENST00000430464

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428936 — 3 exons

Exon	Start	End
ENSE00001632918	77149841	77150100
ENSE00001719839	77147652	77147818
ENSE00004117945	77140791	77140848

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 83.61.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	83.61	gold quality
skeletal muscle tissue	UBERON:0001134	72.51	gold quality
right testis	UBERON:0004534	72.37	gold quality
urinary bladder	UBERON:0001255	68.49	silver quality
calcaneal tendon	UBERON:0003701	67.37	gold quality
testis	UBERON:0000473	66.46	gold quality
left testis	UBERON:0004533	65.50	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.91	gold quality
corpus callosum	UBERON:0002336	63.11	gold quality
primary visual cortex	UBERON:0002436	61.70	gold quality
tonsil	UBERON:0002372	61.56	silver quality
right coronary artery	UBERON:0001625	61.39	gold quality
islet of Langerhans	UBERON:0000006	61.20	gold quality
liver	UBERON:0002107	59.09	gold quality
blood	UBERON:0000178	58.28	gold quality
prefrontal cortex	UBERON:0000451	56.47	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.04	gold quality
right lobe of liver	UBERON:0001114	54.04	gold quality
gastrocnemius	UBERON:0001388	54.00	gold quality
myometrium	UBERON:0001296	53.39	gold quality
multicellular organism	UBERON:0000468	52.85	gold quality
adrenal tissue	UBERON:0018303	52.58	gold quality
ascending aorta	UBERON:0001496	52.54	gold quality
body of stomach	UBERON:0001161	52.27	gold quality
thoracic aorta	UBERON:0001515	51.97	gold quality
stomach	UBERON:0000945	51.63	gold quality
popliteal artery	UBERON:0002250	51.60	gold quality
tibial artery	UBERON:0007610	51.40	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.13	gold quality
descending thoracic aorta	UBERON:0002345	50.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Long noncoding RNA KCNMA1-AS2 regulates the function of colorectal cancer cells and sponges miR-1227-5p. (PMID:39026221)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.