KCNQ1-AS1

Summary

KCNQ1-AS1 (KCNQ1 antisense RNA 1, HGNC:42790) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42790
Approved symbol	KCNQ1-AS1
Name	KCNQ1 antisense RNA 1
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229414
Ensembl biotype	lncRNA
Entrez	338653
RNAcentral	URS00007E3B28 — lncRNA, 1085 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000440887, ENST00000737299, ENST00000737300, ENST00000737301, ENST00000737302, ENST00000737303, ENST00000737304, ENST00000737305

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000440887 — 3 exons

Exon	Start	End
ENSE00001744185	2860990	2861568
ENSE00001756744	2840135	2840442
ENSE00001790381	2858743	2858939

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 59.84.

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right ovary	UBERON:0002118	59.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.55	gold quality
leukocyte	CL:0000738	56.98	gold quality
monocyte	CL:0000576	56.82	gold quality
skeletal muscle tissue	UBERON:0001134	55.74	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.26	gold quality
placenta	UBERON:0001987	53.20	gold quality
cortex of kidney	UBERON:0001225	52.49	gold quality
blood	UBERON:0000178	52.07	silver quality
gall bladder	UBERON:0002110	51.66	gold quality
ovary	UBERON:0000992	51.55	gold quality
bone marrow	UBERON:0002371	51.54	silver quality
prefrontal cortex	UBERON:0000451	51.52	gold quality
left ovary	UBERON:0002119	51.19	gold quality
duodenum	UBERON:0002114	48.93	gold quality
islet of Langerhans	UBERON:0000006	48.71	gold quality
muscle of leg	UBERON:0001383	48.21	silver quality
right adrenal gland	UBERON:0001233	47.46	gold quality
left coronary artery	UBERON:0001626	47.35	gold quality
gastrocnemius	UBERON:0001388	47.20	silver quality
subcutaneous adipose tissue	UBERON:0002190	47.12	gold quality
adrenal gland	UBERON:0002369	47.11	gold quality
left adrenal gland	UBERON:0001234	47.07	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	46.99	gold quality
left adrenal gland cortex	UBERON:0035825	46.99	gold quality
adipose tissue	UBERON:0001013	46.40	gold quality
right adrenal gland cortex	UBERON:0035827	46.22	gold quality
myometrium	UBERON:0001296	46.12	silver quality
omental fat pad	UBERON:0010414	45.53	gold quality
anterior cingulate cortex	UBERON:0009835	45.51	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.