KCNQ5-AS1

Summary

KCNQ5-AS1 (KCNQ5 antisense RNA 1, HGNC:40323) is a long non-coding RNA gene on chromosome 6q13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40323
Approved symbol	KCNQ5-AS1
Name	KCNQ5 antisense RNA 1
Location	6q13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229154
Ensembl biotype	lncRNA
Entrez	100873997
RNAcentral	URS00003639DF — lncRNA, 1101 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000429832, ENST00000654657, ENST00000656650, ENST00000666538, ENST00000837885

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429832 — 5 exons

Exon	Start	End
ENSE00001621202	73136633	73136760
ENSE00001650402	73135287	73135352
ENSE00001655372	73143426	73143514
ENSE00001710498	73134803	73135027
ENSE00001768234	73135567	73136159

Expression profiles

Bgee: expression breadth broad, 92 present calls, max score 88.82.

Top tissues by expression

92 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.82	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.93	gold quality
left testis	UBERON:0004533	72.25	gold quality
testis	UBERON:0000473	71.74	gold quality
right testis	UBERON:0004534	71.46	gold quality
bone marrow cell	CL:0002092	71.05	silver quality
bone marrow	UBERON:0002371	66.23	gold quality
skeletal muscle tissue	UBERON:0001134	66.21	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.74	gold quality
cortical plate	UBERON:0005343	62.47	gold quality
ganglionic eminence	UBERON:0004023	57.17	gold quality
muscle of leg	UBERON:0001383	56.70	gold quality
corpus callosum	UBERON:0002336	56.64	gold quality
gastrocnemius	UBERON:0001388	56.48	gold quality
superior frontal gyrus	UBERON:0002661	55.58	gold quality
urinary bladder	UBERON:0001255	55.13	silver quality
primary visual cortex	UBERON:0002436	54.89	gold quality
adrenal tissue	UBERON:0018303	54.65	gold quality
calcaneal tendon	UBERON:0003701	53.62	silver quality
prefrontal cortex	UBERON:0000451	53.18	gold quality
tonsil	UBERON:0002372	53.12	silver quality
blood	UBERON:0000178	52.64	silver quality
lymph node	UBERON:0000029	51.47	gold quality
multicellular organism	UBERON:0000468	50.74	gold quality
stomach	UBERON:0000945	49.25	gold quality
heart	UBERON:0000948	49.21	gold quality
vermiform appendix	UBERON:0001154	48.62	gold quality
frontal cortex	UBERON:0001870	48.13	gold quality
monocyte	CL:0000576	47.93	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	46.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.