KDM2B-DT

Summary

KDM2B-DT (KDM2B divergent transcript, HGNC:53287) is a long non-coding RNA gene on chromosome 12q24.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53287
Approved symbol	KDM2B-DT
Name	KDM2B divergent transcript
Location	12q24.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256742
Ensembl biotype	lncRNA
Entrez	101928346
RNAcentral	URS00026A1E21 — lncRNA, 1180 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000541574, ENST00000786358, ENST00000786359, ENST00000786360, ENST00000786361, ENST00000786362, ENST00000786363, ENST00000786364, ENST00000786365, ENST00000786366, ENST00000786367, ENST00000786368

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000541574 — 4 exons

Exon	Start	End
ENSE00002259050	121593433	121593547
ENSE00002291066	121580792	121581263
ENSE00004035122	121595914	121597226
ENSE00004035123	121595424	121595554

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 91.67.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9590 / max 29.2792, expressed in 445 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
128431	0.5911	281
128432	0.3461	197
128433	0.0218	11

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.67	silver quality
left testis	UBERON:0004533	82.84	gold quality
right testis	UBERON:0004534	82.38	gold quality
testis	UBERON:0000473	82.04	gold quality
sural nerve	UBERON:0015488	73.27	silver quality
cerebellar hemisphere	UBERON:0002245	68.97	gold quality
cerebellar cortex	UBERON:0002129	68.95	gold quality
cerebellum	UBERON:0002037	68.91	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.42	gold quality
ventricular zone	UBERON:0003053	68.34	gold quality
lymph node	UBERON:0000029	68.30	gold quality
cortical plate	UBERON:0005343	67.54	gold quality
ganglionic eminence	UBERON:0004023	67.42	gold quality
prefrontal cortex	UBERON:0000451	66.23	gold quality
frontal cortex	UBERON:0001870	64.85	gold quality
stromal cell of endometrium	CL:0002255	64.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.42	gold quality
blood	UBERON:0000178	63.94	gold quality
bone marrow cell	CL:0002092	63.83	silver quality
vermiform appendix	UBERON:0001154	63.76	gold quality
right frontal lobe	UBERON:0002810	63.36	gold quality
right uterine tube	UBERON:0001302	63.35	gold quality
cerebral cortex	UBERON:0000956	63.34	gold quality
anterior cingulate cortex	UBERON:0009835	63.24	gold quality
primary visual cortex	UBERON:0002436	63.07	gold quality
tonsil	UBERON:0002372	63.05	gold quality
bone marrow	UBERON:0002371	62.99	gold quality
brain	UBERON:0000955	62.83	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	62.38	gold quality
amygdala	UBERON:0001876	62.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.