KDM5C-IT1

Summary

KDM5C-IT1 (KDM5C intronic transcript 1, HGNC:41384) is a long non-coding RNA gene on chromosome Xp11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41384
Approved symbol	KDM5C-IT1
Name	KDM5C intronic transcript 1
Location	Xp11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235262
Ensembl biotype	lncRNA
Entrez	100874299
RNAcentral	URS000040786B — lncRNA, 755 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000412242

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412242 — 2 exons

Exon	Start	End
ENSE00001758958	53212408	53212739
ENSE00001790398	53214257	53214679

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 73.56.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	73.56	gold quality
colonic epithelium	UBERON:0000397	68.01	silver quality
skeletal muscle tissue	UBERON:0001134	63.65	silver quality
bone marrow	UBERON:0002371	63.65	gold quality
muscle tissue	UBERON:0002385	63.60	silver quality
ventricular zone	UBERON:0003053	62.71	gold quality
tonsil	UBERON:0002372	61.90	silver quality
hindlimb stylopod muscle	UBERON:0004252	59.98	gold quality
monocyte	CL:0000576	55.79	gold quality
blood	UBERON:0000178	54.60	gold quality
uterine cervix	UBERON:0000002	53.39	gold quality
liver	UBERON:0002107	51.97	silver quality
endometrium	UBERON:0001295	51.17	gold quality
urinary bladder	UBERON:0001255	50.37	gold quality
vermiform appendix	UBERON:0001154	50.12	gold quality
adrenal tissue	UBERON:0018303	49.86	silver quality
pancreas	UBERON:0001264	49.32	gold quality
calcaneal tendon	UBERON:0003701	49.03	silver quality
superior frontal gyrus	UBERON:0002661	48.87	gold quality
myometrium	UBERON:0001296	48.57	gold quality
lymph node	UBERON:0000029	48.19	silver quality
muscle of leg	UBERON:0001383	47.73	silver quality
placenta	UBERON:0001987	47.49	gold quality
body of pancreas	UBERON:0001150	47.34	gold quality
thoracic mammary gland	UBERON:0005200	47.33	gold quality
gastrocnemius	UBERON:0001388	47.25	silver quality
prefrontal cortex	UBERON:0000451	47.13	gold quality
kidney	UBERON:0002113	47.12	silver quality
descending thoracic aorta	UBERON:0002345	46.73	gold quality
tibial artery	UBERON:0007610	46.31	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.