KHDC1-AS1

Summary

KHDC1-AS1 (KHDC1 antisense RNA 1, HGNC:55468) is a long non-coding RNA gene on chromosome 6q13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55468
Approved symbol	KHDC1-AS1
Name	KHDC1 antisense RNA 1
Location	6q13
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc-KHDC3L-2
Ensembl gene	ENSG00000229852
Ensembl biotype	lncRNA
Entrez	122539212
RNAcentral	URS00026A1B7F — lncRNA, 4559 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000421315, ENST00000441363, ENST00000442007, ENST00000653052, ENST00000662430, ENST00000671298, ENST00000773755, ENST00000773756, ENST00000773757, ENST00000773758, ENST00000773759

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421315 — 3 exons

Exon	Start	End
ENSE00001629739	73268051	73270527
ENSE00001641758	73290533	73294718
ENSE00001773635	73284658	73284734

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 79.53.

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	79.53	gold quality
ganglionic eminence	UBERON:0004023	79.28	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.83	gold quality
ventricular zone	UBERON:0003053	78.06	gold quality
cerebellum	UBERON:0002037	77.43	gold quality
cerebellar cortex	UBERON:0002129	77.42	gold quality
cerebellar hemisphere	UBERON:0002245	77.34	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.90	gold quality
prefrontal cortex	UBERON:0000451	76.02	gold quality
superior frontal gyrus	UBERON:0002661	75.74	gold quality
thymus	UBERON:0002370	75.31	silver quality
frontal cortex	UBERON:0001870	74.85	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.67	gold quality
cerebral cortex	UBERON:0000956	74.48	gold quality
nucleus accumbens	UBERON:0001882	74.48	gold quality
anterior cingulate cortex	UBERON:0009835	74.46	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.10	gold quality
primary visual cortex	UBERON:0002436	74.00	gold quality
stromal cell of endometrium	CL:0002255	73.96	gold quality
brain	UBERON:0000955	73.74	gold quality
Ammon’s horn	UBERON:0001954	73.61	gold quality
sural nerve	UBERON:0015488	73.55	gold quality
caudate nucleus	UBERON:0001873	73.24	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.13	gold quality
right frontal lobe	UBERON:0002810	73.06	gold quality
putamen	UBERON:0001874	73.05	gold quality
temporal lobe	UBERON:0001871	72.49	gold quality
amygdala	UBERON:0001876	72.44	gold quality
spinal cord	UBERON:0002240	72.44	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.