KIAA0087

Summary

KIAA0087 (KIAA0087 lncRNA, HGNC:22191) is a long non-coding RNA gene on chromosome 7p15.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:22191
Approved symbol	KIAA0087
Name	KIAA0087 lncRNA
Location	7p15.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000122548
Ensembl biotype	lncRNA
OMIM	621321
Entrez	9808
RNAcentral	URS000075EF0D — lncRNA, 4320 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000242109

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000242109 — 2 exons

Exon	Start	End
ENSE00004152774	26533121	26537020
ENSE00004152775	26538406	26538859

Expression profiles

Bgee: expression breadth broad, 91 present calls, max score 80.98.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3005 / max 154.3832, expressed in 26 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
83228	0.2122	17
83227	0.0883	19

Top tissues by expression

206 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	80.98	silver quality
right hemisphere of cerebellum	UBERON:0014890	62.35	gold quality
right uterine tube	UBERON:0001302	62.10	gold quality
cerebellar hemisphere	UBERON:0002245	61.91	gold quality
cerebellar cortex	UBERON:0002129	61.85	gold quality
cerebellum	UBERON:0002037	60.20	gold quality
cortical plate	UBERON:0005343	59.06	silver quality
ganglionic eminence	UBERON:0004023	56.77	silver quality
prefrontal cortex	UBERON:0000451	50.54	gold quality
frontal pole	UBERON:0002795	50.41	gold quality
middle frontal gyrus	UBERON:0002702	50.30	gold quality
paraflocculus	UBERON:0005351	50.18	gold quality
Brodmann (1909) area 10	UBERON:0013541	50.18	gold quality
monocyte	CL:0000576	49.30	silver quality
blood vessel layer	UBERON:0004797	49.29	gold quality
cerebellar vermis	UBERON:0004720	49.25	gold quality
choroid plexus epithelium	UBERON:0003911	48.89	gold quality
nucleus accumbens	UBERON:0001882	47.92	gold quality
metanephric glomerulus	UBERON:0004736	47.83	gold quality
renal glomerulus	UBERON:0000074	47.64	gold quality
gall bladder	UBERON:0002110	47.61	silver quality
periodontal ligament	UBERON:0008266	47.14	gold quality
endometrium epithelium	UBERON:0004811	46.85	gold quality
cranial nerve II	UBERON:0000941	46.75	silver quality
nephron tubule	UBERON:0001231	46.71	gold quality
frontal cortex	UBERON:0001870	46.70	gold quality
fallopian tube	UBERON:0003889	46.57	gold quality
brain	UBERON:0000955	46.42	gold quality
islet of Langerhans	UBERON:0000006	46.40	silver quality
central nervous system	UBERON:0001017	46.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.92

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA KIAA0087 suppresses the progression of osteosarcoma by mediating the SOCS1/JAK2/STAT3 signaling pathway. (PMID:37009803)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.