KIF25-AS1

Summary

KIF25-AS1 (KIF25 antisense RNA 1, HGNC:20953) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20953
Approved symbol	KIF25-AS1
Name	KIF25 antisense RNA 1
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Aliases	HGC6.1.1
Ensembl gene	ENSG00000229921
Ensembl biotype	lncRNA
Entrez	100505879
RNAcentral	URS000075C928 — lncRNA, 1405 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 7 lncRNA, 1 retained_intron

ENST00000414364, ENST00000441716, ENST00000456585, ENST00000538528, ENST00000663121, ENST00000732089, ENST00000732220, ENST00000732221

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414364 — 4 exons

Exon	Start	End
ENSE00001640588	167996238	167996601
ENSE00001739287	167994172	167994464
ENSE00001798785	167996906	167997077
ENSE00002203179	167995513	167996103

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 79.55.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4104 / max 71.7739, expressed in 180 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
76721	0.2702	130
76722	0.1402	73

Top tissues by expression

252 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	79.55	gold quality
endometrium epithelium	UBERON:0004811	75.52	gold quality
frontal pole	UBERON:0002795	73.94	gold quality
paraflocculus	UBERON:0005351	73.18	gold quality
middle frontal gyrus	UBERON:0002702	72.96	gold quality
Brodmann (1909) area 10	UBERON:0013541	66.69	gold quality
cartilage tissue	UBERON:0002418	66.61	silver quality
cerebellar vermis	UBERON:0004720	65.03	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.08	gold quality
ventricular zone	UBERON:0003053	63.02	gold quality
cerebellar cortex	UBERON:0002129	62.88	gold quality
cerebellar hemisphere	UBERON:0002245	62.74	gold quality
cerebellum	UBERON:0002037	62.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.64	gold quality
cortical plate	UBERON:0005343	61.59	gold quality
lower lobe of lung	UBERON:0008949	60.70	silver quality
parotid gland	UBERON:0001831	60.29	gold quality
ganglionic eminence	UBERON:0004023	60.27	gold quality
prefrontal cortex	UBERON:0000451	59.53	gold quality
decidua	UBERON:0002450	58.88	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	58.45	gold quality
pancreatic ductal cell	CL:0002079	58.03	silver quality
esophagus squamous epithelium	UBERON:0006920	57.64	gold quality
apex of heart	UBERON:0002098	57.46	gold quality
myocardium	UBERON:0002349	57.16	gold quality
superficial temporal artery	UBERON:0001614	57.04	gold quality
epithelium of esophagus	UBERON:0001976	57.02	gold quality
endothelial cell	CL:0000115	56.81	gold quality
spinal cord	UBERON:0002240	56.69	gold quality
quadriceps femoris	UBERON:0001377	56.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.