KIF5C-AS1

Summary

KIF5C-AS1 (KIF5C antisense RNA 1, HGNC:40325) is a long non-coding RNA gene on chromosome 2q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40325
Approved symbol	KIF5C-AS1
Name	KIF5C antisense RNA 1
Location	2q23.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231079
Ensembl biotype	lncRNA
Entrez	112267889
RNAcentral	URS0000761AFD — lncRNA, 2592 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000446781, ENST00000601658, ENST00000608822, ENST00000609886

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446781 — 3 exons

Exon	Start	End
ENSE00001773138	148877875	148879866
ENSE00003140419	148885535	148885597
ENSE00003754490	148888287	148888823

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 74.18.

Top tissues by expression

197 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	74.18	gold quality
colonic epithelium	UBERON:0000397	68.64	gold quality
corpus callosum	UBERON:0002336	64.87	gold quality
ganglionic eminence	UBERON:0004023	60.14	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.18	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.75	gold quality
cerebellar cortex	UBERON:0002129	57.28	gold quality
cerebellar hemisphere	UBERON:0002245	57.09	gold quality
monocyte	CL:0000576	57.03	gold quality
cerebellum	UBERON:0002037	56.01	gold quality
right lobe of thyroid gland	UBERON:0001119	51.00	gold quality
adrenal gland	UBERON:0002369	50.50	gold quality
islet of Langerhans	UBERON:0000006	50.29	gold quality
left adrenal gland cortex	UBERON:0035825	50.11	gold quality
prefrontal cortex	UBERON:0000451	49.89	gold quality
left adrenal gland	UBERON:0001234	49.81	gold quality
granulocyte	CL:0000094	49.61	silver quality
pancreas	UBERON:0001264	49.34	gold quality
right adrenal gland	UBERON:0001233	49.03	gold quality
blood	UBERON:0000178	49.02	silver quality
adrenal cortex	UBERON:0001235	48.94	gold quality
lymph node	UBERON:0000029	48.75	gold quality
pituitary gland	UBERON:0000007	48.09	gold quality
right adrenal gland cortex	UBERON:0035827	47.97	gold quality
gall bladder	UBERON:0002110	47.34	gold quality
vermiform appendix	UBERON:0001154	46.84	gold quality
adenohypophysis	UBERON:0002196	46.72	gold quality
adrenal tissue	UBERON:0018303	45.93	silver quality
primary visual cortex	UBERON:0002436	45.90	gold quality
body of pancreas	UBERON:0001150	45.77	silver quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-GEOD-180759	yes	952.09
E-ANND-3	yes	4.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.