KIRREL3-AS2

Summary

KIRREL3-AS2 (KIRREL3 antisense RNA 2, HGNC:42656) is a long non-coding RNA gene on chromosome 11q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42656
Approved symbol	KIRREL3-AS2
Name	KIRREL3 antisense RNA 2
Location	11q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254960
Ensembl biotype	lncRNA
Entrez	100874251
RNAcentral	URS000075C7CB — lncRNA, 500 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000532988, ENST00000578084, ENST00000846008, ENST00000846009, ENST00000846010, ENST00000846011

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000532988 — 3 exons

Exon	Start	End
ENSE00002192887	126944316	126944467
ENSE00004273332	126944928	126945092
ENSE00004273339	126940730	126940924

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 96.39.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0467 / max 35.6357, expressed in 7 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
117526	0.0283	6
117524	0.0093	3
117525	0.0091	3

Top tissues by expression

190 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.39	gold quality
sperm	CL:0000019	88.81	gold quality
left testis	UBERON:0004533	87.40	gold quality
right testis	UBERON:0004534	86.39	gold quality
testis	UBERON:0000473	84.25	gold quality
corpus callosum	UBERON:0002336	73.97	gold quality
colonic epithelium	UBERON:0000397	68.72	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.08	gold quality
medial globus pallidus	UBERON:0002477	61.11	silver quality
islet of Langerhans	UBERON:0000006	56.75	gold quality
globus pallidus	UBERON:0001875	56.67	silver quality
putamen	UBERON:0001874	56.27	gold quality
amygdala	UBERON:0001876	56.14	gold quality
adult organism	UBERON:0007023	55.81	silver quality
anterior cingulate cortex	UBERON:0009835	54.93	gold quality
nucleus accumbens	UBERON:0001882	54.65	gold quality
caudate nucleus	UBERON:0001873	54.19	gold quality
tendon of biceps brachii	UBERON:0008188	53.57	gold quality
gastrocnemius	UBERON:0001388	52.95	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.52	gold quality
prefrontal cortex	UBERON:0000451	52.40	gold quality
lower lobe of lung	UBERON:0008949	51.83	silver quality
calcaneal tendon	UBERON:0003701	51.72	silver quality
cerebellar cortex	UBERON:0002129	51.15	gold quality
cerebellar hemisphere	UBERON:0002245	50.77	gold quality
forebrain	UBERON:0001890	50.28	gold quality
brain	UBERON:0000955	50.19	gold quality
cerebellum	UBERON:0002037	50.14	gold quality
substantia nigra	UBERON:0002038	49.90	gold quality
right hemisphere of cerebellum	UBERON:0014890	49.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.