KLC1-AS1

Summary

KLC1-AS1 (KLC1 antisense RNA 1, HGNC:56065) is a long non-coding RNA gene on chromosome 14q32.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56065
Approved symbol	KLC1-AS1
Name	KLC1 antisense RNA 1
Location	14q32.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246451
Ensembl biotype	lncRNA
Entrez	123706534
RNAcentral	URS000021A8A7 — lncRNA, 1404 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000498989

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000498989 — 2 exons

Exon	Start	End
ENSE00001532859	103682362	103682607
ENSE00001977353	103682858	103684015

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 87.90.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	87.90	gold quality
cerebellar hemisphere	UBERON:0002245	87.29	gold quality
cerebellar cortex	UBERON:0002129	87.26	gold quality
cerebellum	UBERON:0002037	87.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	87.15	gold quality
sural nerve	UBERON:0015488	81.74	gold quality
bone marrow cell	CL:0002092	81.10	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.08	gold quality
uterine cervix	UBERON:0000002	80.35	gold quality
tonsil	UBERON:0002372	80.28	gold quality
skeletal muscle tissue	UBERON:0001134	80.01	gold quality
stromal cell of endometrium	CL:0002255	79.91	gold quality
ascending aorta	UBERON:0001496	79.42	gold quality
right coronary artery	UBERON:0001625	79.40	gold quality
thoracic aorta	UBERON:0001515	79.12	gold quality
myometrium	UBERON:0001296	79.08	gold quality
body of uterus	UBERON:0009853	78.98	gold quality
tibial nerve	UBERON:0001323	78.82	gold quality
pituitary gland	UBERON:0000007	78.79	gold quality
superior frontal gyrus	UBERON:0002661	78.77	gold quality
primary visual cortex	UBERON:0002436	78.64	gold quality
bone marrow	UBERON:0002371	78.46	gold quality
blood	UBERON:0000178	78.34	gold quality
vagina	UBERON:0000996	78.28	gold quality
popliteal artery	UBERON:0002250	78.11	gold quality
tibial artery	UBERON:0007610	78.08	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	78.04	gold quality
ectocervix	UBERON:0012249	78.03	gold quality
apex of heart	UBERON:0002098	78.00	gold quality
descending thoracic aorta	UBERON:0002345	77.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.