KLC2-AS2

Summary

KLC2-AS2 (KLC2 antisense RNA 2, HGNC:55515) is a long non-coding RNA gene on chromosome 11q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55515
Approved symbol	KLC2-AS2
Name	KLC2 antisense RNA 2
Location	11q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254762
Ensembl biotype	lncRNA
Entrez	105369351
RNAcentral	URS00026A1A0D — lncRNA, 550 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000533287

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000533287 — 2 exons

Exon	Start	End
ENSE00002166930	66268055	66268129
ENSE00002177436	66267635	66267831

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 87.96.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.96	gold quality
ganglionic eminence	UBERON:0004023	80.59	gold quality
prefrontal cortex	UBERON:0000451	79.61	gold quality
ventricular zone	UBERON:0003053	78.85	gold quality
cortical plate	UBERON:0005343	77.39	gold quality
frontal cortex	UBERON:0001870	77.07	gold quality
primary visual cortex	UBERON:0002436	70.21	gold quality
skeletal muscle tissue	UBERON:0001134	70.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.23	gold quality
bone marrow	UBERON:0002371	67.04	gold quality
monocyte	CL:0000576	66.23	gold quality
Ammon’s horn	UBERON:0001954	66.10	gold quality
temporal lobe	UBERON:0001871	66.00	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.99	gold quality
superior frontal gyrus	UBERON:0002661	64.28	gold quality
corpus callosum	UBERON:0002336	64.05	gold quality
brain	UBERON:0000955	64.01	gold quality
islet of Langerhans	UBERON:0000006	63.27	gold quality
amygdala	UBERON:0001876	63.19	gold quality
blood	UBERON:0000178	62.62	gold quality
placenta	UBERON:0001987	62.19	gold quality
muscle of leg	UBERON:0001383	61.90	gold quality
liver	UBERON:0002107	61.85	gold quality
gastrocnemius	UBERON:0001388	61.78	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.68	gold quality
nucleus accumbens	UBERON:0001882	61.62	gold quality
pancreas	UBERON:0001264	60.93	gold quality
lymph node	UBERON:0000029	60.86	gold quality
descending thoracic aorta	UBERON:0002345	60.48	gold quality
substantia nigra	UBERON:0002038	60.33	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.23

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.