KLC4-AS1

Summary

KLC4-AS1 (KLC4 antisense RNA 1, HGNC:55228) is a long non-coding RNA gene on chromosome 6p21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55228
Approved symbol	KLC4-AS1
Name	KLC4 antisense RNA 1
Location	6p21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272170
Ensembl biotype	lncRNA
Entrez	112267958
RNAcentral	URS0002A4CE6B — lncRNA, 1250 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000606123, ENST00000758810, ENST00000758811, ENST00000758812, ENST00000758813, ENST00000758814, ENST00000758815, ENST00000758816, ENST00000758817, ENST00000758818, ENST00000758819, ENST00000758820, ENST00000758821

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606123 — 2 exons

Exon	Start	End
ENSE00004111056	43077056	43077263
ENSE00004111057	43074331	43075267

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 84.38.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.38	gold quality
mucosa of transverse colon	UBERON:0004991	75.34	gold quality
right lobe of liver	UBERON:0001114	74.80	gold quality
bone marrow cell	CL:0002092	74.72	gold quality
ventricular zone	UBERON:0003053	73.78	gold quality
cerebellar hemisphere	UBERON:0002245	72.08	gold quality
cerebellar cortex	UBERON:0002129	72.00	gold quality
cerebellum	UBERON:0002037	71.93	gold quality
cortical plate	UBERON:0005343	71.86	gold quality
liver	UBERON:0002107	71.08	gold quality
stromal cell of endometrium	CL:0002255	71.04	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.99	gold quality
left lobe of thyroid gland	UBERON:0001120	69.62	gold quality
metanephros cortex	UBERON:0010533	69.55	gold quality
ganglionic eminence	UBERON:0004023	69.38	gold quality
thyroid gland	UBERON:0002046	69.17	gold quality
right lobe of thyroid gland	UBERON:0001119	68.71	gold quality
lower esophagus mucosa	UBERON:0035834	68.65	gold quality
left ovary	UBERON:0002119	68.36	gold quality
endocervix	UBERON:0000458	68.17	gold quality
ectocervix	UBERON:0012249	67.99	gold quality
ovary	UBERON:0000992	67.80	gold quality
bone marrow	UBERON:0002371	67.74	gold quality
myometrium	UBERON:0001296	67.72	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.49	gold quality
body of uterus	UBERON:0009853	67.45	gold quality
prostate gland	UBERON:0002367	67.12	gold quality
smooth muscle tissue	UBERON:0001135	66.78	gold quality
mucosa of stomach	UBERON:0001199	66.64	gold quality
right ovary	UBERON:0002118	66.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.