KLF2-DT

Summary

KLF2-DT (KLF2 divergent transcript, HGNC:55304) is a long non-coding RNA gene on chromosome 19p13.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55304
Approved symbol	KLF2-DT
Name	KLF2 divergent transcript
Location	19p13.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267275
Ensembl biotype	lncRNA
Entrez	118827812
RNAcentral	URS00026A2721 — lncRNA, 727 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000588799, ENST00000588945, ENST00000810104, ENST00000810105, ENST00000810106, ENST00000810107, ENST00000810108, ENST00000810109, ENST00000810110, ENST00000810111, ENST00000810112, ENST00000810113, ENST00000810114

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000588799 — 2 exons

Exon	Start	End
ENSE00004206638	16324307	16324543
ENSE00004206650	16283352	16283721

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 81.27.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.27	gold quality
right uterine tube	UBERON:0001302	71.16	gold quality
granulocyte	CL:0000094	71.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.88	gold quality
bone marrow cell	CL:0002092	65.54	silver quality
monocyte	CL:0000576	61.19	gold quality
blood	UBERON:0000178	58.68	gold quality
bone marrow	UBERON:0002371	58.61	gold quality
skeletal muscle tissue	UBERON:0001134	58.36	gold quality
fallopian tube	UBERON:0003889	57.24	gold quality
lymph node	UBERON:0000029	55.79	gold quality
calcaneal tendon	UBERON:0003701	55.12	gold quality
superior frontal gyrus	UBERON:0002661	55.11	gold quality
smooth muscle tissue	UBERON:0001135	54.98	gold quality
sural nerve	UBERON:0015488	53.87	silver quality
Ammon’s horn	UBERON:0001954	52.58	gold quality
prefrontal cortex	UBERON:0000451	52.49	gold quality
nucleus accumbens	UBERON:0001882	51.12	gold quality
vermiform appendix	UBERON:0001154	50.64	gold quality
liver	UBERON:0002107	50.44	gold quality
hindlimb stylopod muscle	UBERON:0004252	50.06	gold quality
islet of Langerhans	UBERON:0000006	49.55	gold quality
kidney	UBERON:0002113	49.30	gold quality
left uterine tube	UBERON:0001303	49.26	gold quality
amygdala	UBERON:0001876	49.26	gold quality
ovary	UBERON:0000992	48.74	gold quality
left ovary	UBERON:0002119	48.60	gold quality
right lung	UBERON:0002167	48.57	gold quality
right ovary	UBERON:0002118	48.50	gold quality
muscle of leg	UBERON:0001383	48.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.