KLF7-IT1

Summary

KLF7-IT1 (KLF7 intronic transcript 1, HGNC:41355) is a long non-coding RNA gene on chromosome 2q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41355
Approved symbol	KLF7-IT1
Name	KLF7 intronic transcript 1
Location	2q33.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237892
Ensembl biotype	lncRNA
Entrez	100874272
RNAcentral	URS000033DA52 — lncRNA, 655 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000428777

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428777 — 2 exons

Exon	Start	End
ENSE00001683851	207120884	207120996
ENSE00001760215	207121503	207122044

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 92.76.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.76	gold quality
bone marrow	UBERON:0002371	84.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.90	silver quality
bone marrow cell	CL:0002092	79.06	gold quality
corpus callosum	UBERON:0002336	78.77	gold quality
calcaneal tendon	UBERON:0003701	77.97	gold quality
monocyte	CL:0000576	77.20	gold quality
sural nerve	UBERON:0015488	72.92	gold quality
colonic epithelium	UBERON:0000397	69.18	gold quality
skeletal muscle tissue	UBERON:0001134	68.59	gold quality
smooth muscle tissue	UBERON:0001135	68.34	gold quality
blood	UBERON:0000178	68.30	gold quality
subcutaneous adipose tissue	UBERON:0002190	67.01	gold quality
adipose tissue	UBERON:0001013	65.91	gold quality
ganglionic eminence	UBERON:0004023	65.72	gold quality
islet of Langerhans	UBERON:0000006	65.34	gold quality
omental fat pad	UBERON:0010414	64.51	gold quality
gall bladder	UBERON:0002110	63.67	gold quality
urinary bladder	UBERON:0001255	63.16	gold quality
adrenal tissue	UBERON:0018303	62.96	gold quality
lower esophagus mucosa	UBERON:0035834	62.71	gold quality
lung	UBERON:0002048	62.26	gold quality
thoracic mammary gland	UBERON:0005200	61.71	gold quality
mucosa of stomach	UBERON:0001199	61.51	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.77	gold quality
upper lobe of left lung	UBERON:0008952	60.75	gold quality
cortical plate	UBERON:0005343	59.97	gold quality
lymph node	UBERON:0000029	59.77	gold quality
tonsil	UBERON:0002372	59.77	gold quality
vermiform appendix	UBERON:0001154	59.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.