KLHL14-AS1

Summary

KLHL14-AS1 (KLHL14 antisense RNA 1, HGNC:58976) is a long non-coding RNA gene on chromosome 18q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58976
Approved symbol	KLHL14-AS1
Name	KLHL14 antisense RNA 1
Location	18q12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.428
Ensembl gene	ENSG00000228835
Ensembl biotype	lncRNA
Entrez	105372055

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000426194

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426194 — 4 exons

Exon	Start	End
ENSE00001602685	32770954	32771108
ENSE00001603692	32773315	32774413
ENSE00001621295	32769795	32769967
ENSE00001764265	32772054	32772287

Expression profiles

Bgee: expression breadth broad, 82 present calls, max score 85.57.

Top tissues by expression

82 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.57	silver quality
right uterine tube	UBERON:0001302	81.94	gold quality
bone marrow cell	CL:0002092	69.47	silver quality
pancreas	UBERON:0001264	66.50	silver quality
right lobe of thyroid gland	UBERON:0001119	66.15	gold quality
thyroid gland	UBERON:0002046	65.40	gold quality
left lobe of thyroid gland	UBERON:0001120	64.49	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.57	gold quality
fallopian tube	UBERON:0003889	63.06	gold quality
cortical plate	UBERON:0005343	61.36	gold quality
endometrium	UBERON:0001295	58.39	gold quality
bone marrow	UBERON:0002371	58.26	silver quality
tonsil	UBERON:0002372	56.18	gold quality
ganglionic eminence	UBERON:0004023	55.49	silver quality
lymph node	UBERON:0000029	54.73	gold quality
liver	UBERON:0002107	53.50	silver quality
spleen	UBERON:0002106	52.54	gold quality
kidney	UBERON:0002113	52.46	gold quality
prefrontal cortex	UBERON:0000451	52.24	silver quality
saliva-secreting gland	UBERON:0001044	52.19	gold quality
urinary bladder	UBERON:0001255	51.43	silver quality
blood	UBERON:0000178	50.65	silver quality
metanephros cortex	UBERON:0010533	50.62	gold quality
multicellular organism	UBERON:0000468	50.41	gold quality
cortex of kidney	UBERON:0001225	50.36	gold quality
endocervix	UBERON:0000458	50.12	gold quality
monocyte	CL:0000576	50.01	silver quality
frontal cortex	UBERON:0001870	49.94	silver quality
left uterine tube	UBERON:0001303	49.33	gold quality
superior frontal gyrus	UBERON:0002661	49.31	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.93

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.