KLHL6-AS1

Summary

KLHL6-AS1 (KLHL6 antisense RNA 1, HGNC:40850) is a long non-coding RNA gene on chromosome 3q27.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40850
Approved symbol	KLHL6-AS1
Name	KLHL6 antisense RNA 1
Location	3q27.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242522
Ensembl biotype	lncRNA
Entrez	100874019
RNAcentral	URS0000759990 — lncRNA, 517 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000491676

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000491676 — 2 exons

Exon	Start	End
ENSE00004259728	183548701	183548963
ENSE00004259729	183552053	183552379

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 98.06.

Top tissues by expression

107 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar vermis	UBERON:0004720	98.06	gold quality
quadriceps femoris	UBERON:0001377	97.07	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.60	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.49	gold quality
colonic epithelium	UBERON:0000397	70.22	gold quality
liver	UBERON:0002107	70.09	gold quality
bone marrow cell	CL:0002092	69.52	silver quality
skeletal muscle tissue	UBERON:0001134	68.64	silver quality
right lobe of liver	UBERON:0001114	67.79	gold quality
tonsil	UBERON:0002372	66.27	gold quality
duodenum	UBERON:0002114	64.85	gold quality
bone marrow	UBERON:0002371	63.03	gold quality
thymus	UBERON:0002370	60.45	silver quality
kidney	UBERON:0002113	59.13	gold quality
adult mammalian kidney	UBERON:0000082	58.41	gold quality
urinary bladder	UBERON:0001255	58.16	gold quality
monocyte	CL:0000576	57.86	gold quality
lymph node	UBERON:0000029	57.02	gold quality
uterine cervix	UBERON:0000002	56.88	silver quality
blood	UBERON:0000178	56.88	gold quality
cortex of kidney	UBERON:0001225	56.55	gold quality
prefrontal cortex	UBERON:0000451	56.01	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.67	gold quality
placenta	UBERON:0001987	54.62	gold quality
vermiform appendix	UBERON:0001154	52.61	gold quality
gall bladder	UBERON:0002110	52.01	gold quality
islet of Langerhans	UBERON:0000006	51.26	gold quality
temporal lobe	UBERON:0001871	50.85	gold quality
cerebellum	UBERON:0002037	50.47	silver quality
pancreas	UBERON:0001264	50.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.