KLHL7-DT

Summary

KLHL7-DT (KLHL7 divergent transcript, HGNC:43431) is a long non-coding RNA gene on chromosome 7p15.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43431
Approved symbol	KLHL7-DT
Name	KLHL7 divergent transcript
Location	7p15.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	PLATAK
Ensembl gene	ENSG00000230658
Ensembl biotype	lncRNA
Entrez	100775104
RNAcentral	URS00003C5D0A — lncRNA, 2564 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000419813, ENST00000662806, ENST00000753833, ENST00000753834

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419813 — 3 exons

Exon	Start	End
ENSE00001630687	23100375	23103578
ENSE00001700934	23104250	23104317
ENSE00003872021	23105553	23105702

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 75.58.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0235 / max 29.2792, expressed in 608 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
83098	0.7286	441
83097	0.2949	148

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.58	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.32	gold quality
corpus callosum	UBERON:0002336	65.18	gold quality
calcaneal tendon	UBERON:0003701	61.89	gold quality
sural nerve	UBERON:0015488	61.28	gold quality
cortical plate	UBERON:0005343	61.05	gold quality
ganglionic eminence	UBERON:0004023	59.81	gold quality
ventricular zone	UBERON:0003053	59.67	gold quality
islet of Langerhans	UBERON:0000006	58.80	gold quality
stromal cell of endometrium	CL:0002255	58.49	gold quality
tonsil	UBERON:0002372	58.25	gold quality
adrenal tissue	UBERON:0018303	57.31	gold quality
smooth muscle tissue	UBERON:0001135	56.97	gold quality
lymph node	UBERON:0000029	56.25	gold quality
right uterine tube	UBERON:0001302	55.74	gold quality
bone marrow	UBERON:0002371	54.38	gold quality
popliteal artery	UBERON:0002250	54.06	gold quality
tibial artery	UBERON:0007610	54.06	gold quality
skeletal muscle tissue	UBERON:0001134	54.04	silver quality
right adrenal gland	UBERON:0001233	54.01	gold quality
endometrium	UBERON:0001295	53.96	gold quality
testis	UBERON:0000473	53.94	gold quality
right coronary artery	UBERON:0001625	53.68	gold quality
adrenal gland	UBERON:0002369	53.62	gold quality
left adrenal gland cortex	UBERON:0035825	53.37	gold quality
left adrenal gland	UBERON:0001234	53.34	gold quality
prefrontal cortex	UBERON:0000451	53.29	gold quality
pancreas	UBERON:0001264	53.28	gold quality
monocyte	CL:0000576	53.24	silver quality
amygdala	UBERON:0001876	53.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.