KRT10-AS1

Summary

KRT10-AS1 (KRT10 antisense RNA 1, HGNC:28305) is a long non-coding RNA gene on chromosome 17q21.2.

Predicted to be located in membrane.

Source: NCBI Gene 147184 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28305
Approved symbol	KRT10-AS1
Name	KRT10 antisense RNA 1
Location	17q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC21518
Ensembl gene	ENSG00000167920
Ensembl biotype	lncRNA
Entrez	147184
RNAcentral	URS0000E60A4D — lncRNA, 2073 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 24 — 24 lncRNA

ENST00000301665, ENST00000436612, ENST00000654043, ENST00000662074, ENST00000666187, ENST00000668620, ENST00000670968, ENST00000671399, ENST00000692645, ENST00000719695, ENST00000719696, ENST00000719697, ENST00000719698, ENST00000719699, ENST00000719700, ENST00000719701, ENST00000719702, ENST00000719703, ENST00000719704, ENST00000719705, ENST00000719706, ENST00000719707, ENST00000719708, ENST00000719709

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000301665 — 3 exons

Exon	Start	End
ENSE00001118390	40833115	40833199
ENSE00004037714	40819098	40819208
ENSE00004037743	40834382	40836271

Expression profiles

Bgee: expression breadth ubiquitous, 234 present calls, max score 97.86.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 8.4645 / max 143.1427, expressed in 1642 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
160808	6.0845	1611
160810	2.2618	1042
160809	0.1182	29

Top tissues by expression

248 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	97.86	gold quality
right testis	UBERON:0004534	97.69	gold quality
pancreatic ductal cell	CL:0002079	97.62	gold quality
parotid gland	UBERON:0001831	97.55	gold quality
testis	UBERON:0000473	96.57	gold quality
sperm	CL:0000019	96.46	gold quality
adult organism	UBERON:0007023	95.73	gold quality
epithelial cell of pancreas	CL:0000083	94.77	gold quality
skin of leg	UBERON:0001511	94.51	gold quality
upper arm skin	UBERON:0004263	94.07	gold quality
zone of skin	UBERON:0000014	93.15	gold quality
skin of abdomen	UBERON:0001416	93.03	gold quality
oviduct epithelium	UBERON:0004804	92.58	gold quality
tibia	UBERON:0000979	91.25	gold quality
endothelial cell	CL:0000115	91.22	gold quality
corpus epididymis	UBERON:0004359	90.30	gold quality
islet of Langerhans	UBERON:0000006	90.17	gold quality
body of pancreas	UBERON:0001150	89.93	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	89.32	gold quality
pancreas	UBERON:0001264	89.24	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.22	gold quality
esophagus squamous epithelium	UBERON:0006920	88.93	gold quality
amniotic fluid	UBERON:0000173	88.81	gold quality
saliva-secreting gland	UBERON:0001044	88.25	gold quality
gingival epithelium	UBERON:0001949	88.13	gold quality
germinal epithelium of ovary	UBERON:0001304	87.74	gold quality
palpebral conjunctiva	UBERON:0001812	87.52	gold quality
upper leg skin	UBERON:0004262	87.10	gold quality
right lobe of liver	UBERON:0001114	86.93	gold quality
right lobe of thyroid gland	UBERON:0001119	86.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.