KRTAP5-AS1

Summary

KRTAP5-AS1 (KRTAP5-1/KRTAP5-2 antisense RNA 1, HGNC:27877) is a long non-coding RNA gene on chromosome 11p15.5.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27877
Approved symbol	KRTAP5-AS1
Name	KRTAP5-1/KRTAP5-2 antisense RNA 1
Location	11p15.5
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233930
Ensembl biotype	lncRNA
Entrez	338651
RNAcentral	URS00005C6188 — lncRNA, 2265 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000424148, ENST00000524947, ENST00000532922, ENST00000534077, ENST00000659213, ENST00000792906

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424148 — 2 exons

Exon	Start	End
ENSE00001727651	1572741	1573068
ENSE00002211956	1597248	1599184

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 84.55.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8820 / max 58.6158, expressed in 443 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
112468	0.4248	234
112469	0.1798	70
112470	0.1632	85
112467	0.1142	50

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellum	UBERON:0002037	84.55	gold quality
cerebellar cortex	UBERON:0002129	84.52	gold quality
cerebellar hemisphere	UBERON:0002245	84.46	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.11	gold quality
superior frontal gyrus	UBERON:0002661	81.95	gold quality
prefrontal cortex	UBERON:0000451	78.79	gold quality
primary visual cortex	UBERON:0002436	78.43	gold quality
frontal cortex	UBERON:0001870	78.27	gold quality
right frontal lobe	UBERON:0002810	76.85	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	75.95	gold quality
cerebral cortex	UBERON:0000956	75.44	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.30	gold quality
anterior cingulate cortex	UBERON:0009835	75.08	gold quality
brain	UBERON:0000955	73.71	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.54	silver quality
mucosa of transverse colon	UBERON:0004991	71.77	gold quality
nucleus accumbens	UBERON:0001882	71.24	gold quality
sural nerve	UBERON:0015488	71.03	gold quality
hypothalamus	UBERON:0001898	71.02	gold quality
putamen	UBERON:0001874	70.39	gold quality
caudate nucleus	UBERON:0001873	70.17	gold quality
cortical plate	UBERON:0005343	70.03	gold quality
body of pancreas	UBERON:0001150	69.51	gold quality
pancreas	UBERON:0001264	69.20	gold quality
temporal lobe	UBERON:0001871	67.58	gold quality
islet of Langerhans	UBERON:0000006	67.53	gold quality
granulocyte	CL:0000094	67.35	gold quality
Ammon’s horn	UBERON:0001954	67.32	gold quality
amygdala	UBERON:0001876	67.30	gold quality
gall bladder	UBERON:0002110	67.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.