L1CAM-AS1

Summary

L1CAM-AS1 (L1CAM antisense RNA 1, HGNC:55247) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55247
Approved symbol	L1CAM-AS1
Name	L1CAM antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Aliases	LCA10
Ensembl gene	ENSG00000273769
Ensembl biotype	lncRNA
Entrez	100996465
RNAcentral	URS000081210C — lncRNA, 1392 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000618311, ENST00000807566

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000618311 — 7 exons

Exon	Start	End
ENSE00003723133	153883711	153883896
ENSE00003723970	153880672	153880718
ENSE00003727840	153885808	153885977
ENSE00003735636	153885363	153885436
ENSE00003742218	153883948	153884273
ENSE00003743911	153888497	153888990
ENSE00003751855	153886963	153887057

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 67.11.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
leukocyte	CL:0000738	67.11	gold quality
sural nerve	UBERON:0015488	65.75	gold quality
ganglionic eminence	UBERON:0004023	59.41	gold quality
cortical plate	UBERON:0005343	59.24	gold quality
ventricular zone	UBERON:0003053	58.44	silver quality
right hemisphere of cerebellum	UBERON:0014890	56.50	gold quality
cerebellar hemisphere	UBERON:0002245	56.08	gold quality
cerebellum	UBERON:0002037	56.05	gold quality
cerebellar cortex	UBERON:0002129	56.00	gold quality
tibial nerve	UBERON:0001323	52.85	gold quality
liver	UBERON:0002107	51.85	silver quality
skeletal muscle tissue	UBERON:0001134	51.23	silver quality
blood	UBERON:0000178	50.63	silver quality
prefrontal cortex	UBERON:0000451	49.03	silver quality
lymph node	UBERON:0000029	48.69	silver quality
brain	UBERON:0000955	48.54	gold quality
placenta	UBERON:0001987	47.21	silver quality
right lobe of liver	UBERON:0001114	46.60	silver quality
muscle of leg	UBERON:0001383	46.48	silver quality
gall bladder	UBERON:0002110	46.02	silver quality
islet of Langerhans	UBERON:0000006	45.94	silver quality
vermiform appendix	UBERON:0001154	45.85	silver quality
gastrocnemius	UBERON:0001388	45.58	silver quality
muscle layer of sigmoid colon	UBERON:0035805	45.56	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.55	gold quality
lower esophagus	UBERON:0013473	45.53	gold quality
esophagus	UBERON:0001043	44.64	gold quality
ovary	UBERON:0000992	44.56	silver quality
frontal cortex	UBERON:0001870	44.50	gold quality
myometrium	UBERON:0001296	44.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.