L3MBTL4-AS1

Summary

L3MBTL4-AS1 (L3MBTL4 antisense RNA 1, HGNC:51320) is a long non-coding RNA gene on chromosome 18p11.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51320
Approved symbol	L3MBTL4-AS1
Name	L3MBTL4 antisense RNA 1
Location	18p11.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000264707
Ensembl biotype	lncRNA
Entrez	101927150
RNAcentral	URS000075CEE6 — lncRNA, 2072 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000578427

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000578427 — 3 exons

Exon	Start	End
ENSE00002703786	6259160	6260934
ENSE00002711814	6258659	6258796
ENSE00002724399	6256747	6256877

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 77.97.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3182 / max 54.2742, expressed in 100 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
169255	0.3182	100

Top tissues by expression

224 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.97	silver quality
pancreatic ductal cell	CL:0002079	74.96	silver quality
colonic epithelium	UBERON:0000397	74.30	silver quality
tendon of biceps brachii	UBERON:0008188	69.53	gold quality
sural nerve	UBERON:0015488	67.77	gold quality
upper arm skin	UBERON:0004263	65.55	gold quality
buccal mucosa cell	CL:0002336	61.67	silver quality
tendon	UBERON:0000043	61.55	gold quality
myocardium	UBERON:0002349	60.81	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	60.72	gold quality
mammary duct	UBERON:0001765	59.75	gold quality
epithelium of mammary gland	UBERON:0003244	59.73	gold quality
monocyte	CL:0000576	59.72	gold quality
cortical plate	UBERON:0005343	59.42	gold quality
amniotic fluid	UBERON:0000173	59.40	gold quality
ileal mucosa	UBERON:0000331	59.34	silver quality
calcaneal tendon	UBERON:0003701	59.19	gold quality
substantia nigra pars reticulata	UBERON:0001966	58.94	gold quality
medial globus pallidus	UBERON:0002477	58.91	silver quality
substantia nigra pars compacta	UBERON:0001965	58.41	silver quality
layer of synovial tissue	UBERON:0007616	58.27	gold quality
globus pallidus	UBERON:0001875	58.24	silver quality
lateral nuclear group of thalamus	UBERON:0002736	57.78	gold quality
ventricular zone	UBERON:0003053	57.78	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	57.35	gold quality
corpus callosum	UBERON:0002336	57.07	gold quality
lymph node	UBERON:0000029	57.04	gold quality
deltoid	UBERON:0001476	56.62	gold quality
epithelial cell of pancreas	CL:0000083	56.47	gold quality
lateral globus pallidus	UBERON:0002476	56.45	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.