LAMA4-AS1

Summary

LAMA4-AS1 (LAMA4 antisense RNA 1, HGNC:40333) is a long non-coding RNA gene on chromosome 6q21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40333
Approved symbol	LAMA4-AS1
Name	LAMA4 antisense RNA 1
Location	6q21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226440
Ensembl biotype	lncRNA
Entrez	101927640
RNAcentral	URS000075ADCE — lncRNA, 536 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000433684, ENST00000585450, ENST00000588837, ENST00000590293, ENST00000590584, ENST00000590804, ENST00000627025, ENST00000628122, ENST00000629766

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433684 — 3 exons

Exon	Start	End
ENSE00001629597	112236779	112236916
ENSE00001692398	112236093	112236638
ENSE00003760976	112306329	112307009

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 82.88.

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lower esophagus muscularis layer	UBERON:0035833	82.88	gold quality
lower esophagus	UBERON:0013473	82.82	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	78.93	gold quality
left uterine tube	UBERON:0001303	78.16	gold quality
tibial nerve	UBERON:0001323	77.23	gold quality
omental fat pad	UBERON:0010414	76.13	gold quality
peritoneum	UBERON:0002358	76.03	gold quality
calcaneal tendon	UBERON:0003701	75.19	gold quality
smooth muscle tissue	UBERON:0001135	75.09	gold quality
adrenal tissue	UBERON:0018303	74.56	gold quality
adipose tissue of abdominal region	UBERON:0007808	74.19	gold quality
body of uterus	UBERON:0009853	73.94	gold quality
gall bladder	UBERON:0002110	73.78	gold quality
muscle layer of sigmoid colon	UBERON:0035805	73.78	gold quality
esophagus	UBERON:0001043	73.25	gold quality
endocervix	UBERON:0000458	71.96	gold quality
sural nerve	UBERON:0015488	71.31	gold quality
apex of heart	UBERON:0002098	70.37	gold quality
upper lobe of left lung	UBERON:0008952	70.36	gold quality
ectocervix	UBERON:0012249	69.06	gold quality
popliteal artery	UBERON:0002250	68.77	gold quality
tibial artery	UBERON:0007610	68.75	gold quality
upper lobe of lung	UBERON:0008948	68.42	gold quality
cortical plate	UBERON:0005343	68.41	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.08	gold quality
ganglionic eminence	UBERON:0004023	67.74	gold quality
heart left ventricle	UBERON:0002084	67.57	gold quality
bone marrow cell	CL:0002092	67.53	silver quality
lower esophagus mucosa	UBERON:0035834	67.41	gold quality
cardiac ventricle	UBERON:0002082	66.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.