LAMA5-AS1

Summary

LAMA5-AS1 (LAMA5 antisense RNA 1, HGNC:40334) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40334
Approved symbol	LAMA5-AS1
Name	LAMA5 antisense RNA 1
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228812
Ensembl biotype	lncRNA
Entrez	101928158
RNAcentral	URS000075ED30 — lncRNA, 838 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000456721, ENST00000477848, ENST00000478167, ENST00000487421, ENST00000702270, ENST00000702333

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456721 — 2 exons

Exon	Start	End
ENSE00003984698	62352970	62353208
ENSE00004208343	62356192	62356482

Expression profiles

Bgee: expression breadth ubiquitous, 173 present calls, max score 93.26.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1434 / max 14.0907, expressed in 58 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
185723	0.1434	58

Top tissues by expression

221 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	93.26	gold quality
tendon of biceps brachii	UBERON:0008188	91.88	gold quality
vena cava	UBERON:0004087	86.73	gold quality
right lobe of liver	UBERON:0001114	85.71	gold quality
cerebellar vermis	UBERON:0004720	84.91	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	81.48	silver quality
myocardium	UBERON:0002349	81.45	silver quality
medial globus pallidus	UBERON:0002477	80.43	gold quality
liver	UBERON:0002107	80.35	gold quality
tendon	UBERON:0000043	80.17	gold quality
sural nerve	UBERON:0015488	79.01	gold quality
globus pallidus	UBERON:0001875	78.46	silver quality
upper arm skin	UBERON:0004263	77.79	gold quality
pharyngeal mucosa	UBERON:0000355	77.01	silver quality
sperm	CL:0000019	76.55	silver quality
body of tongue	UBERON:0011876	76.35	gold quality
heart left ventricle	UBERON:0002084	76.21	gold quality
cardiac ventricle	UBERON:0002082	76.08	gold quality
trachea	UBERON:0003126	76.02	silver quality
pons	UBERON:0000988	75.66	silver quality
left ventricle myocardium	UBERON:0006566	75.42	gold quality
apex of heart	UBERON:0002098	75.36	gold quality
cardiac atrium	UBERON:0002081	75.13	gold quality
right atrium auricular region	UBERON:0006631	75.10	gold quality
pericardium	UBERON:0002407	75.06	gold quality
cardiac muscle of right atrium	UBERON:0003379	75.06	gold quality
nipple	UBERON:0002030	74.08	silver quality
gastrocnemius	UBERON:0001388	73.84	gold quality
cartilage tissue	UBERON:0002418	73.80	silver quality
heart	UBERON:0000948	73.74	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.