LAPTM4A-DT

Summary

LAPTM4A-DT (LAPTM4A divergent transcript, HGNC:54382) is a long non-coding RNA gene on chromosome 2p24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54382
Approved symbol	LAPTM4A-DT
Name	LAPTM4A divergent transcript
Location	2p24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223734
Ensembl biotype	lncRNA
Entrez	105373463
RNAcentral	URS00026A2100 — lncRNA, 1040 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000452342, ENST00000688203, ENST00000849369, ENST00000849370, ENST00000849371, ENST00000849372, ENST00000849373, ENST00000849374, ENST00000849375, ENST00000849376

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452342 — 3 exons

Exon	Start	End
ENSE00004279801	20066516	20066800
ENSE00004279802	20052114	20052494
ENSE00004279816	20054285	20054549

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 94.71.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2725 / max 13.5325, expressed in 128 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
19117	0.2725	128

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.71	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	91.63	gold quality
right testis	UBERON:0004534	78.12	gold quality
left testis	UBERON:0004533	77.09	gold quality
testis	UBERON:0000473	77.07	gold quality
hindlimb stylopod muscle	UBERON:0004252	67.90	gold quality
cortical plate	UBERON:0005343	66.24	gold quality
ganglionic eminence	UBERON:0004023	64.86	gold quality
monocyte	CL:0000576	56.73	gold quality
granulocyte	CL:0000094	55.43	gold quality
prefrontal cortex	UBERON:0000451	54.86	gold quality
lymph node	UBERON:0000029	54.38	gold quality
islet of Langerhans	UBERON:0000006	53.63	gold quality
right lung	UBERON:0002167	52.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.23	gold quality
bone marrow	UBERON:0002371	52.20	gold quality
vermiform appendix	UBERON:0001154	51.50	gold quality
descending thoracic aorta	UBERON:0002345	51.40	gold quality
blood	UBERON:0000178	50.34	silver quality
calcaneal tendon	UBERON:0003701	49.51	silver quality
muscle of leg	UBERON:0001383	49.40	gold quality
placenta	UBERON:0001987	49.35	gold quality
endometrium	UBERON:0001295	48.97	gold quality
liver	UBERON:0002107	48.76	silver quality
adult mammalian kidney	UBERON:0000082	48.41	gold quality
gastrocnemius	UBERON:0001388	47.82	gold quality
multicellular organism	UBERON:0000468	47.72	gold quality
frontal cortex	UBERON:0001870	47.63	gold quality
primary visual cortex	UBERON:0002436	47.46	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.