LARGE1-AS1

Summary

LARGE1-AS1 (LARGE1 antisense RNA 1, HGNC:55162) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55162
Approved symbol	LARGE1-AS1
Name	LARGE1 antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273082
Ensembl biotype	lncRNA
Entrez	107985565
RNAcentral	URS0002A1CBF7 — lncRNA, 956 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000610170

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610170 — 2 exons

Exon	Start	End
ENSE00004154950	33922407	33923049
ENSE00004154951	33921211	33921523

Expression profiles

Bgee: expression breadth ubiquitous, 120 present calls, max score 95.77.

Top tissues by expression

120 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	95.77	gold quality
tibial nerve	UBERON:0001323	72.58	gold quality
ventricular zone	UBERON:0003053	71.81	gold quality
cortical plate	UBERON:0005343	70.71	gold quality
right lobe of liver	UBERON:0001114	70.22	gold quality
liver	UBERON:0002107	68.81	gold quality
left ovary	UBERON:0002119	68.53	gold quality
ovary	UBERON:0000992	67.52	gold quality
anterior cingulate cortex	UBERON:0009835	66.69	gold quality
right ovary	UBERON:0002118	66.22	gold quality
gall bladder	UBERON:0002110	65.30	gold quality
left adrenal gland cortex	UBERON:0035825	65.25	gold quality
prefrontal cortex	UBERON:0000451	64.56	gold quality
islet of Langerhans	UBERON:0000006	64.24	gold quality
mucosa of transverse colon	UBERON:0004991	63.53	gold quality
superior frontal gyrus	UBERON:0002661	63.38	gold quality
myometrium	UBERON:0001296	62.44	gold quality
left adrenal gland	UBERON:0001234	62.35	gold quality
cerebral cortex	UBERON:0000956	62.25	gold quality
frontal cortex	UBERON:0001870	62.23	gold quality
lymph node	UBERON:0000029	62.22	gold quality
pituitary gland	UBERON:0000007	61.97	gold quality
body of stomach	UBERON:0001161	61.84	gold quality
right uterine tube	UBERON:0001302	61.82	gold quality
primary visual cortex	UBERON:0002436	61.79	gold quality
amygdala	UBERON:0001876	61.77	gold quality
stomach	UBERON:0000945	61.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.60	gold quality
urinary bladder	UBERON:0001255	61.59	gold quality
adenohypophysis	UBERON:0002196	61.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.25

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.