LARS2-AS1

Summary

LARS2-AS1 (LARS2 antisense RNA 1, HGNC:40796) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40796
Approved symbol	LARS2-AS1
Name	LARS2 antisense RNA 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232455
Ensembl biotype	lncRNA
Entrez	100885795
RNAcentral	URS000075AC11 — lncRNA, 1854 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000442534, ENST00000777455

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000442534 — 4 exons

Exon	Start	End
ENSE00001596458	45506912	45506982
ENSE00001609638	45495244	45495500
ENSE00001764104	45509357	45509545
ENSE00002072472	45483974	45484031

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 80.92.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0407 / max 13.5506, expressed in 18 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41896	0.0407	18

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.92	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.76	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.45	gold quality
skeletal muscle tissue	UBERON:0001134	59.50	gold quality
bone marrow	UBERON:0002371	56.91	gold quality
gall bladder	UBERON:0002110	55.85	gold quality
monocyte	CL:0000576	54.32	gold quality
calcaneal tendon	UBERON:0003701	53.06	silver quality
islet of Langerhans	UBERON:0000006	52.52	gold quality
lymph node	UBERON:0000029	52.41	gold quality
blood	UBERON:0000178	52.01	gold quality
placenta	UBERON:0001987	51.33	gold quality
prefrontal cortex	UBERON:0000451	51.32	gold quality
endocervix	UBERON:0000458	51.30	gold quality
uterine cervix	UBERON:0000002	50.96	gold quality
vermiform appendix	UBERON:0001154	50.70	gold quality
muscle of leg	UBERON:0001383	49.99	gold quality
corpus callosum	UBERON:0002336	49.53	silver quality
adrenal tissue	UBERON:0018303	49.43	silver quality
liver	UBERON:0002107	49.09	silver quality
gastrocnemius	UBERON:0001388	48.37	gold quality
mucosa of stomach	UBERON:0001199	48.23	gold quality
kidney	UBERON:0002113	47.91	gold quality
cortex of kidney	UBERON:0001225	47.78	gold quality
myometrium	UBERON:0001296	47.75	gold quality
right lobe of liver	UBERON:0001114	46.81	silver quality
primary visual cortex	UBERON:0002436	46.40	silver quality
right atrium auricular region	UBERON:0006631	46.25	gold quality
adenohypophysis	UBERON:0002196	46.14	gold quality
heart	UBERON:0000948	46.01	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.