LBX1-AS1

Summary

LBX1-AS1 (LBX1 antisense RNA 1, HGNC:48678) is a long non-coding RNA gene on chromosome 10q24.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48678
Approved symbol	LBX1-AS1
Name	LBX1 antisense RNA 1
Location	10q24.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ41350
Ensembl gene	ENSG00000227128
Ensembl biotype	lncRNA
Entrez	399806
RNAcentral	URS000075A252 — lncRNA, 1332 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 25 — 23 lncRNA, 2 retained_intron

ENST00000430651, ENST00000434878, ENST00000454527, ENST00000456391, ENST00000546988, ENST00000547077, ENST00000823572, ENST00000823573, ENST00000823574, ENST00000823575, ENST00000823576, ENST00000823577, ENST00000823578, ENST00000823579, ENST00000823580, ENST00000823581, ENST00000823582, ENST00000823583, ENST00000823584, ENST00000823585, ENST00000823586, ENST00000823587, ENST00000823588, ENST00000823589, ENST00000823590

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430651 — 2 exons

Exon	Start	End
ENSE00004232120	101237939	101238849
ENSE00004232137	101236068	101237710

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 87.16.

Top tissues by expression

208 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle of leg	UBERON:0001383	87.16	gold quality
gastrocnemius	UBERON:0001388	86.41	gold quality
islet of Langerhans	UBERON:0000006	85.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.61	gold quality
vastus lateralis	UBERON:0001379	81.74	silver quality
quadriceps femoris	UBERON:0001377	80.12	silver quality
skeletal muscle tissue	UBERON:0001134	78.29	gold quality
biceps brachii	UBERON:0001507	77.39	silver quality
left testis	UBERON:0004533	73.54	gold quality
right testis	UBERON:0004534	73.06	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	71.17	silver quality
testis	UBERON:0000473	71.01	gold quality
upper arm skin	UBERON:0004263	68.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	68.00	gold quality
cerebellar hemisphere	UBERON:0002245	67.02	gold quality
cerebellar cortex	UBERON:0002129	67.01	gold quality
cerebellum	UBERON:0002037	65.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.65	gold quality
tibialis anterior	UBERON:0001385	61.35	silver quality
nasal cavity epithelium	UBERON:0005384	60.56	gold quality
adult organism	UBERON:0007023	59.33	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.16	gold quality
sperm	CL:0000019	58.71	gold quality
left ventricle myocardium	UBERON:0006566	57.50	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.22	gold quality
spinal cord	UBERON:0002240	56.96	gold quality
pancreatic ductal cell	CL:0002079	55.80	silver quality
heart right ventricle	UBERON:0002080	55.59	gold quality
cardiac muscle of right atrium	UBERON:0003379	55.01	gold quality
lower lobe of lung	UBERON:0008949	54.90	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.