LCMT1-AS2

Summary

LCMT1-AS2 (LCMT1 antisense RNA 2, HGNC:51178) is a long non-coding RNA gene on chromosome 16p12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51178
Approved symbol	LCMT1-AS2
Name	LCMT1 antisense RNA 2
Location	16p12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260034
Ensembl biotype	lncRNA
Entrez	100506655
RNAcentral	URS000075E662 — lncRNA, 2611 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000562280, ENST00000565214, ENST00000749041, ENST00000749042

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000562280 — 3 exons

Exon	Start	End
ENSE00002616502	25146248	25148239
ENSE00004092333	25140573	25140858
ENSE00004092336	25148706	25149051

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 93.79.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5668 / max 378.5173, expressed in 37 samples.

FANTOM5 promoters (9 alternative TSS)

Promoter ID	TPM avg	Samples expressed
156809	0.3170	16
156814	0.1393	19
156810	0.0384	8
156807	0.0176	9
156813	0.0149	5
156808	0.0121	5
156815	0.0109	5
156811	0.0105	3
156812	0.0061	3

Top tissues by expression

201 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
placenta	UBERON:0001987	93.79	gold quality
colonic epithelium	UBERON:0000397	72.62	gold quality
bone marrow cell	CL:0002092	70.65	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	68.38	silver quality
adrenal tissue	UBERON:0018303	65.66	gold quality
pancreatic ductal cell	CL:0002079	61.04	silver quality
buccal mucosa cell	CL:0002336	60.77	gold quality
ganglionic eminence	UBERON:0004023	60.00	gold quality
smooth muscle tissue	UBERON:0001135	59.46	gold quality
ventricular zone	UBERON:0003053	59.35	gold quality
calcaneal tendon	UBERON:0003701	59.15	gold quality
sural nerve	UBERON:0015488	58.99	silver quality
tonsil	UBERON:0002372	56.07	silver quality
ileal mucosa	UBERON:0000331	55.75	silver quality
tibialis anterior	UBERON:0001385	54.92	silver quality
epithelial cell of pancreas	CL:0000083	54.78	gold quality
epithelium of nasopharynx	UBERON:0001951	54.57	gold quality
corpus callosum	UBERON:0002336	54.54	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
bone marrow	UBERON:0002371	53.77	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
tendon	UBERON:0000043	53.07	silver quality
stromal cell of endometrium	CL:0002255	52.49	silver quality
monocyte	CL:0000576	52.01	silver quality
germinal epithelium of ovary	UBERON:0001304	51.53	gold quality
deltoid	UBERON:0001476	51.30	gold quality
kidney	UBERON:0002113	51.09	gold quality
body of uterus	UBERON:0009853	50.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.