LENG8-AS1

Summary

LENG8-AS1 (LENG8 antisense RNA 1, HGNC:40705) is a long non-coding RNA gene on chromosome 19q13.42.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40705
Approved symbol	LENG8-AS1
Name	LENG8 antisense RNA 1
Location	19q13.42
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226696
Ensembl biotype	lncRNA
Entrez	104355426
RNAcentral	URS00007E335F — lncRNA, 892 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000416022, ENST00000429922, ENST00000448978, ENST00000652740, ENST00000686924, ENST00000716545, ENST00000839975, ENST00000839976, ENST00000839977, ENST00000839978, ENST00000839979, ENST00000839980, ENST00000839981, ENST00000839982, ENST00000839983, ENST00000839984, ENST00000839985, ENST00000839986

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416022 — 3 exons

Exon	Start	End
ENSE00004262776	54444794	54445179
ENSE00004262780	54438375	54438556
ENSE00004262805	54448165	54448602

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 89.11.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.3933 / max 100.1468, expressed in 1408 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
182650	3.9465	1331
182649	0.4468	223

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	89.11	gold quality
left ovary	UBERON:0002119	87.65	gold quality
ovary	UBERON:0000992	86.77	gold quality
right ovary	UBERON:0002118	86.65	gold quality
right lobe of thyroid gland	UBERON:0001119	86.31	gold quality
tibial nerve	UBERON:0001323	86.19	gold quality
body of pancreas	UBERON:0001150	85.91	gold quality
pituitary gland	UBERON:0000007	85.59	gold quality
thyroid gland	UBERON:0002046	85.54	gold quality
left lobe of thyroid gland	UBERON:0001120	85.44	gold quality
endocervix	UBERON:0000458	85.21	gold quality
adenohypophysis	UBERON:0002196	84.80	gold quality
ectocervix	UBERON:0012249	84.72	gold quality
uterine cervix	UBERON:0000002	84.31	gold quality
popliteal artery	UBERON:0002250	84.09	gold quality
tibial artery	UBERON:0007610	84.09	gold quality
cortex of kidney	UBERON:0001225	83.99	gold quality
body of uterus	UBERON:0009853	83.93	gold quality
thoracic mammary gland	UBERON:0005200	83.70	gold quality
monocyte	CL:0000576	83.69	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.39	gold quality
apex of heart	UBERON:0002098	83.35	gold quality
prostate gland	UBERON:0002367	83.27	gold quality
pancreas	UBERON:0001264	83.23	gold quality
sural nerve	UBERON:0015488	83.18	gold quality
cerebellum	UBERON:0002037	83.11	gold quality
cerebellar cortex	UBERON:0002129	83.09	gold quality
vagina	UBERON:0000996	83.08	gold quality
cerebellar hemisphere	UBERON:0002245	83.03	gold quality
small intestine Peyer’s patch	UBERON:0003454	82.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.