LGI2-AS1

Summary

LGI2-AS1 (LGI2 antisense RNA 1, HGNC:58746) is a long non-coding RNA gene on chromosome 4p15.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58746
Approved symbol	LGI2-AS1
Name	LGI2 antisense RNA 1
Location	4p15.2
Locus type	RNA, long non-coding
Status	Approved
Entrez	124900684

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000003788 (4:25040179 C>T), RS1000035096 (4:25040490 C>T), RS10001303 (4:25032553 T>A,C,G), RS1000186614 (4:25032340 A>G), RS1000553366 (4:25030879 C>G,T), RS1000861924 (4:25035604 T>C,G), RS1001130649 (4:25037065 CA>C,CAA), RS1001335168 (4:25035906 G>C,T), RS1001342052 (4:25031638 A>C), RS1001538124 (4:25031409 C>A,T), RS1001885817 (4:25036310 C>G), RS1001934349 (4:25038161 A>C), RS1001943597 (4:25041397 G>T), RS10020219 (4:25033078 C>T), RS10021870 (4:25028690 G>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.