LGR4-AS1

Summary

LGR4-AS1 (LGR4 antisense RNA 1, HGNC:40629) is a long non-coding RNA gene on chromosome 11p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40629
Approved symbol	LGR4-AS1
Name	LGR4 antisense RNA 1
Location	11p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000254862
Ensembl biotype	lncRNA
Entrez	105376671
RNAcentral	URS0000812121 — lncRNA, 1348 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000525833, ENST00000529258, ENST00000715842

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525833 — 5 exons

Exon	Start	End
ENSE00002143991	27471729	27471832
ENSE00002162827	27472778	27472957
ENSE00002164927	27475769	27476221
ENSE00002175579	27473168	27473651
ENSE00002195468	27474418	27474546

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 84.15.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.15	silver quality
cerebellar cortex	UBERON:0002129	65.70	gold quality
cerebellar hemisphere	UBERON:0002245	65.70	gold quality
cerebellum	UBERON:0002037	65.62	gold quality
right hemisphere of cerebellum	UBERON:0014890	64.55	gold quality
right uterine tube	UBERON:0001302	63.57	gold quality
ganglionic eminence	UBERON:0004023	61.40	gold quality
bone marrow	UBERON:0002371	57.56	gold quality
body of pancreas	UBERON:0001150	56.70	gold quality
subcutaneous adipose tissue	UBERON:0002190	55.82	gold quality
pancreas	UBERON:0001264	55.34	gold quality
adipose tissue	UBERON:0001013	55.32	gold quality
caudate nucleus	UBERON:0001873	55.21	gold quality
rectum	UBERON:0001052	54.81	gold quality
adrenal tissue	UBERON:0018303	54.81	gold quality
endometrium	UBERON:0001295	54.75	gold quality
left ovary	UBERON:0002119	54.68	gold quality
ovary	UBERON:0000992	54.66	gold quality
skeletal muscle tissue	UBERON:0001134	54.61	gold quality
leukocyte	CL:0000738	54.58	silver quality
omental fat pad	UBERON:0010414	54.40	gold quality
monocyte	CL:0000576	54.32	silver quality
muscle of leg	UBERON:0001383	54.23	gold quality
nucleus accumbens	UBERON:0001882	54.15	gold quality
gastrocnemius	UBERON:0001388	54.07	gold quality
smooth muscle tissue	UBERON:0001135	53.90	gold quality
prefrontal cortex	UBERON:0000451	53.86	gold quality
primary visual cortex	UBERON:0002436	53.85	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.85	gold quality
thoracic mammary gland	UBERON:0005200	53.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.