LHX2-AS1

Summary

LHX2-AS1 (LHX2 antisense RNA 1, HGNC:56163) is a long non-coding RNA gene on chromosome 9q33.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56163
Approved symbol	LHX2-AS1
Name	LHX2 antisense RNA 1
Location	9q33.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236668
Ensembl biotype	lncRNA
Entrez	100505588
RNAcentral	URS00004E737D — lncRNA, 2146 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000453529, ENST00000722527, ENST00000722528, ENST00000722529

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453529 — 2 exons

Exon	Start	End
ENSE00004043237	124006277	124008091
ENSE00004043239	124009066	124009541

Expression profiles

Bgee: expression breadth broad, 42 present calls, max score 76.27.

Top tissues by expression

42 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.27	silver quality
right hemisphere of cerebellum	UBERON:0014890	73.17	gold quality
cerebellar hemisphere	UBERON:0002245	72.11	gold quality
ventricular zone	UBERON:0003053	70.97	gold quality
prefrontal cortex	UBERON:0000451	70.62	gold quality
ganglionic eminence	UBERON:0004023	70.09	gold quality
frontal cortex	UBERON:0001870	69.78	gold quality
anterior cingulate cortex	UBERON:0009835	69.28	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.24	gold quality
right frontal lobe	UBERON:0002810	69.08	gold quality
cerebral cortex	UBERON:0000956	68.25	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.27	gold quality
cortical plate	UBERON:0005343	66.47	gold quality
superior frontal gyrus	UBERON:0002661	65.73	gold quality
amygdala	UBERON:0001876	65.47	gold quality
temporal lobe	UBERON:0001871	65.36	gold quality
adenohypophysis	UBERON:0002196	64.34	gold quality
liver	UBERON:0002107	63.02	silver quality
brain	UBERON:0000955	62.26	gold quality
Ammon’s horn	UBERON:0001954	62.24	gold quality
primary visual cortex	UBERON:0002436	62.11	gold quality
pituitary gland	UBERON:0000007	60.42	gold quality
multicellular organism	UBERON:0000468	57.43	gold quality
blood	UBERON:0000178	57.23	gold quality
putamen	UBERON:0001874	55.88	gold quality
caudate nucleus	UBERON:0001873	52.91	gold quality
nucleus accumbens	UBERON:0001882	51.81	gold quality
substantia nigra	UBERON:0002038	50.12	gold quality
colon	UBERON:0001155	46.34	silver quality
right atrium auricular region	UBERON:0006631	45.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.