LHX8-AS1

Summary

LHX8-AS1 (LHX8 antisense RNA 1, HGNC:41213) is a long non-coding RNA gene on chromosome 1p31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41213
Approved symbol	LHX8-AS1
Name	LHX8 antisense RNA 1
Location	1p31.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224149
Ensembl biotype	lncRNA
Entrez	131216852
RNAcentral	URS00026A23B7 — lncRNA, 4331 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000427892

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427892 — 2 exons

Exon	Start	End
ENSE00001632718	75132354	75132576
ENSE00001682824	75129974	75131953

Expression profiles

Bgee: expression breadth broad, 23 present calls, max score 55.89.

Top tissues by expression

23 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
heart	UBERON:0000948	55.89	silver quality
urinary bladder	UBERON:0001255	50.52	gold quality
anterior cingulate cortex	UBERON:0009835	49.86	gold quality
tonsil	UBERON:0002372	48.88	gold quality
hypothalamus	UBERON:0001898	48.55	gold quality
putamen	UBERON:0001874	48.09	gold quality
caudate nucleus	UBERON:0001873	47.98	gold quality
saliva-secreting gland	UBERON:0001044	47.02	gold quality
gall bladder	UBERON:0002110	47.01	gold quality
minor salivary gland	UBERON:0001830	46.95	gold quality
nucleus accumbens	UBERON:0001882	45.89	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	45.75	gold quality
esophagus	UBERON:0001043	43.64	gold quality
Brodmann (1909) area 9	UBERON:0013540	41.74	silver quality
prostate gland	UBERON:0002367	41.19	gold quality
thyroid gland	UBERON:0002046	40.84	silver quality
esophagus mucosa	UBERON:0002469	40.68	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	40.06	silver quality
amygdala	UBERON:0001876	39.62	silver quality
left lobe of thyroid gland	UBERON:0001120	39.06	silver quality
substantia nigra	UBERON:0002038	37.19	silver quality
left testis	UBERON:0004533	26.56	silver quality
right testis	UBERON:0004534	24.99	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.