LIF-AS1

Summary

LIF-AS1 (LIF antisense RNA 1, HGNC:53473) is a long non-coding RNA gene on chromosome 22q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53473
Approved symbol	LIF-AS1
Name	LIF antisense RNA 1
Location	22q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	Lnc-LIF-AS, RP1-102K2.6
Ensembl gene	ENSG00000232530
Ensembl biotype	lncRNA
Entrez	110806283
RNAcentral	URS00001747AF — lncRNA, 808 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000447565, ENST00000843023, ENST00000843024, ENST00000843025

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000447565 — 3 exons

Exon	Start	End
ENSE00001638748	30239194	30239278
ENSE00001644668	30239691	30239821
ENSE00001644963	30239947	30240538

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 76.69.

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.69	gold quality
sural nerve	UBERON:0015488	74.97	gold quality
ganglionic eminence	UBERON:0004023	60.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.37	gold quality
right adrenal gland cortex	UBERON:0035827	56.59	gold quality
blood	UBERON:0000178	56.31	gold quality
bone marrow	UBERON:0002371	56.13	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	54.72	gold quality
islet of Langerhans	UBERON:0000006	53.22	gold quality
lymph node	UBERON:0000029	53.07	gold quality
apex of heart	UBERON:0002098	52.86	gold quality
gall bladder	UBERON:0002110	52.64	gold quality
monocyte	CL:0000576	52.59	silver quality
stromal cell of endometrium	CL:0002255	51.98	silver quality
right adrenal gland	UBERON:0001233	51.24	gold quality
granulocyte	CL:0000094	51.18	silver quality
adult mammalian kidney	UBERON:0000082	50.24	gold quality
placenta	UBERON:0001987	49.79	gold quality
adrenal gland	UBERON:0002369	49.59	gold quality
left adrenal gland	UBERON:0001234	49.10	gold quality
liver	UBERON:0002107	48.98	silver quality
left adrenal gland cortex	UBERON:0035825	48.80	gold quality
endometrium	UBERON:0001295	48.39	gold quality
vermiform appendix	UBERON:0001154	48.38	gold quality
fallopian tube	UBERON:0003889	47.83	gold quality
superior frontal gyrus	UBERON:0002661	47.81	gold quality
muscle of leg	UBERON:0001383	47.76	silver quality
primary visual cortex	UBERON:0002436	47.37	silver quality
omental fat pad	UBERON:0010414	46.73	gold quality
gastrocnemius	UBERON:0001388	46.68	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.85

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.