LIG1-AS1

Summary

LIG1-AS1 (LIG1 antisense RNA 1, HGNC:58602) is a long non-coding RNA gene on chromosome 19q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58602
Approved symbol	LIG1-AS1
Name	LIG1 antisense RNA 1
Location	19q13.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269321
Ensembl biotype	lncRNA
Entrez	107985293

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000594589

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000594589 — 2 exons

Exon	Start	End
ENSE00003036408	48147266	48147413
ENSE00003081214	48145908	48146118

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 87.04.

Top tissues by expression

97 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.04	gold quality
right testis	UBERON:0004534	81.59	gold quality
left testis	UBERON:0004533	79.42	gold quality
testis	UBERON:0000473	78.64	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.00	gold quality
bone marrow	UBERON:0002371	67.60	gold quality
corpus callosum	UBERON:0002336	65.42	gold quality
lymph node	UBERON:0000029	62.15	gold quality
monocyte	CL:0000576	60.68	gold quality
tonsil	UBERON:0002372	57.59	silver quality
islet of Langerhans	UBERON:0000006	57.46	gold quality
blood	UBERON:0000178	56.18	gold quality
descending thoracic aorta	UBERON:0002345	55.65	gold quality
endometrium	UBERON:0001295	55.43	gold quality
superior frontal gyrus	UBERON:0002661	55.33	gold quality
muscle of leg	UBERON:0001383	54.95	gold quality
gastrocnemius	UBERON:0001388	54.53	gold quality
primary visual cortex	UBERON:0002436	54.48	gold quality
right coronary artery	UBERON:0001625	54.12	gold quality
right lung	UBERON:0002167	54.12	gold quality
prefrontal cortex	UBERON:0000451	53.70	gold quality
right lobe of liver	UBERON:0001114	52.48	gold quality
kidney	UBERON:0002113	52.38	gold quality
placenta	UBERON:0001987	52.34	gold quality
cerebellar cortex	UBERON:0002129	51.77	gold quality
adult mammalian kidney	UBERON:0000082	51.64	gold quality
adrenal tissue	UBERON:0018303	51.63	gold quality
cerebellar hemisphere	UBERON:0002245	51.59	gold quality
tibial artery	UBERON:0007610	51.49	gold quality
heart left ventricle	UBERON:0002084	51.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.