LIM2-AS1

Summary

LIM2-AS1 (LIM2 and SIGLEC10 antisense RNA 1, HGNC:56004) is a long non-coding RNA gene on chromosome 19q13.41.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56004
Approved symbol	LIM2-AS1
Name	LIM2 and SIGLEC10 antisense RNA 1
Location	19q13.41
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000268889
Ensembl biotype	lncRNA
Entrez	105372446
RNAcentral	URS0002A33657 — lncRNA, 1526 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000600765, ENST00000687249, ENST00000738637, ENST00000738638, ENST00000738639, ENST00000738640, ENST00000738641, ENST00000738642, ENST00000738643, ENST00000738644, ENST00000738645, ENST00000738646, ENST00000738647

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000600765 — 2 exons

Exon	Start	End
ENSE00004073955	51394421	51394595
ENSE00004073962	51403200	51403650

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 71.64.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ventricular zone	UBERON:0003053	71.64	gold quality
bone marrow cell	CL:0002092	70.59	silver quality
granulocyte	CL:0000094	68.97	gold quality
bone marrow	UBERON:0002371	67.78	gold quality
ganglionic eminence	UBERON:0004023	64.54	gold quality
skeletal muscle tissue	UBERON:0001134	59.40	gold quality
blood	UBERON:0000178	58.74	gold quality
lymph node	UBERON:0000029	54.71	gold quality
duodenum	UBERON:0002114	53.32	gold quality
islet of Langerhans	UBERON:0000006	53.23	gold quality
vermiform appendix	UBERON:0001154	52.70	gold quality
placenta	UBERON:0001987	52.49	gold quality
monocyte	CL:0000576	52.22	gold quality
prefrontal cortex	UBERON:0000451	50.60	gold quality
pancreas	UBERON:0001264	50.33	gold quality
endometrium	UBERON:0001295	49.98	gold quality
mucosa of transverse colon	UBERON:0004991	49.17	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.64	gold quality
liver	UBERON:0002107	46.37	silver quality
multicellular organism	UBERON:0000468	45.54	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	44.83	gold quality
frontal cortex	UBERON:0001870	44.81	gold quality
cerebral cortex	UBERON:0000956	44.76	gold quality
right lobe of liver	UBERON:0001114	44.73	silver quality
muscle of leg	UBERON:0001383	44.67	silver quality
adrenal tissue	UBERON:0018303	44.65	silver quality
lung	UBERON:0002048	44.59	gold quality
skin of abdomen	UBERON:0001416	44.32	gold quality
spleen	UBERON:0002106	44.20	silver quality
gastrocnemius	UBERON:0001388	43.94	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.