LIMD1-AS1

Summary

LIMD1-AS1 (LIMD1 antisense RNA 1, HGNC:44107) is a long non-coding RNA gene on chromosome 3p21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44107
Approved symbol	LIMD1-AS1
Name	LIMD1 antisense RNA 1
Location	3p21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230530
Ensembl biotype	lncRNA
Entrez	644714
RNAcentral	URS000075C13B — lncRNA, 2316 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000427644, ENST00000429798, ENST00000655322, ENST00000658801, ENST00000820543

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000427644 — 2 exons

Exon	Start	End
ENSE00001666369	45679043	45680071
ENSE00001682325	45688376	45688882

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 91.73.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1110 / max 5.8120, expressed in 64 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
41900	0.1110	64

Top tissues by expression

254 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lung	UBERON:0002167	91.73	gold quality
upper lobe of left lung	UBERON:0008952	89.82	gold quality
ventricular zone	UBERON:0003053	88.90	gold quality
right lobe of liver	UBERON:0001114	87.32	gold quality
gastrocnemius	UBERON:0001388	86.93	gold quality
upper lobe of lung	UBERON:0008948	86.65	gold quality
right coronary artery	UBERON:0001625	86.64	gold quality
apex of heart	UBERON:0002098	86.59	gold quality
right lobe of thyroid gland	UBERON:0001119	85.92	gold quality
muscle of leg	UBERON:0001383	85.88	gold quality
mucosa of transverse colon	UBERON:0004991	85.85	gold quality
popliteal artery	UBERON:0002250	85.63	gold quality
tibial artery	UBERON:0007610	85.62	gold quality
ganglionic eminence	UBERON:0004023	85.52	gold quality
left lobe of thyroid gland	UBERON:0001120	85.46	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.56	gold quality
granulocyte	CL:0000094	84.49	gold quality
aorta	UBERON:0000947	84.46	gold quality
mucosa of stomach	UBERON:0001199	84.08	gold quality
descending thoracic aorta	UBERON:0002345	84.00	gold quality
tibial nerve	UBERON:0001323	83.97	gold quality
rectum	UBERON:0001052	83.88	gold quality
left coronary artery	UBERON:0001626	83.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.76	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	83.75	gold quality
thyroid gland	UBERON:0002046	83.68	gold quality
ascending aorta	UBERON:0001496	83.56	gold quality
thoracic aorta	UBERON:0001515	83.50	gold quality
minor salivary gland	UBERON:0001830	83.30	gold quality
heart left ventricle	UBERON:0002084	83.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LIMD1-AS1 suppressed non-small cell lung cancer progression through stabilizing LIMD1 mRNA via hnRNP U. (PMID:32239804)
• Super-enhancer-driven lncRNA LIMD1-AS1 activated by CDK7 promotes glioma progression. (PMID:37385987)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.