LINC00092

Summary

LINC00092 (long intergenic non-protein coding RNA 92, HGNC:31408) is a long non-coding RNA gene on chromosome 9q22.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31408
Approved symbol	LINC00092
Name	long intergenic non-protein coding RNA 92
Location	9q22.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA346B7.1
Ensembl gene	ENSG00000225194
Ensembl biotype	lncRNA
Entrez	100188953
RNAcentral	URS0000ABD8C4 — lncRNA, 1861 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000412122, ENST00000580908, ENST00000583864, ENST00000648648, ENST00000649879, ENST00000650007, ENST00000685262, ENST00000785823

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412122 — 2 exons

Exon	Start	End
ENSE00001619125	96021585	96021831
ENSE00001794949	96019724	96021281

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 83.18.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2242 / max 61.1787, expressed in 76 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
101587	0.1497	32
101585	0.0509	40
101586	0.0237	9

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	83.18	gold quality
cerebellar cortex	UBERON:0002129	81.18	gold quality
cerebellar hemisphere	UBERON:0002245	81.07	gold quality
cerebellum	UBERON:0002037	79.70	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.94	gold quality
amygdala	UBERON:0001876	76.93	gold quality
mucosa of stomach	UBERON:0001199	75.91	gold quality
anterior cingulate cortex	UBERON:0009835	75.55	gold quality
right frontal lobe	UBERON:0002810	75.47	gold quality
nucleus accumbens	UBERON:0001882	75.32	gold quality
putamen	UBERON:0001874	74.79	gold quality
hypothalamus	UBERON:0001898	74.37	gold quality
caudate nucleus	UBERON:0001873	73.98	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.16	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.16	gold quality
medial globus pallidus	UBERON:0002477	72.88	gold quality
right lobe of thyroid gland	UBERON:0001119	72.37	gold quality
substantia nigra	UBERON:0002038	72.13	gold quality
left lobe of thyroid gland	UBERON:0001120	71.82	gold quality
spinal cord	UBERON:0002240	71.78	gold quality
granulocyte	CL:0000094	71.71	gold quality
tibial nerve	UBERON:0001323	71.36	gold quality
thyroid gland	UBERON:0002046	71.26	gold quality
right lung	UBERON:0002167	70.06	gold quality
midbrain	UBERON:0001891	70.05	gold quality
popliteal artery	UBERON:0002250	69.91	gold quality
tibial artery	UBERON:0007610	69.91	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.66	gold quality
body of stomach	UBERON:0001161	69.64	gold quality
globus pallidus	UBERON:0001875	69.52	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 4)

• High LINC00092 expression is associated with metastatic progression of Ovarian Cancer. (PMID:28087599)
• Long non-coding RNA Linc00092 inhibits cardiac fibroblast activation by altering glycolysis in an ERK-dependent manner. (PMID:32653641)
• LINC00092 Suppresses the Malignant Progression of Breast Invasive Ductal Carcinoma Through Modulating SFRP1 Expression by Sponging miR-1827. (PMID:35343265)
• MYB/LINC00092 regulatory axis promotes the progression of papillary thyroid carcinoma. (PMID:38497387)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.