LINC00106

Summary

LINC00106 (long intergenic non-protein coding RNA 106, HGNC:31843) is a long non-coding RNA gene on chromosome Xp22.33 and Yp11.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31843
Approved symbol	LINC00106
Name	long intergenic non-protein coding RNA 106
Location	Xp22.33 and Yp11.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	OTTHUMG00000021061
Ensembl gene	ENSG00000236871
Ensembl biotype	lncRNA
Entrez	751580
RNAcentral	URS0000812135 — lncRNA, 380 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000430235, ENST00000434938, ENST00000747767, ENST00000747768

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430235 — 3 exons

Exon	Start	End
ENSE00001640360	1399367	1399402
ENSE00001690734	1397025	1397224
ENSE00001762861	1398825	1398958

Expression profiles

Bgee: expression breadth ubiquitous, 169 present calls, max score 94.73.

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of thyroid gland	UBERON:0001119	94.73	gold quality
adenohypophysis	UBERON:0002196	94.19	gold quality
left lobe of thyroid gland	UBERON:0001120	93.72	gold quality
right adrenal gland cortex	UBERON:0035827	93.70	gold quality
pituitary gland	UBERON:0000007	93.34	gold quality
right uterine tube	UBERON:0001302	93.08	gold quality
left adrenal gland cortex	UBERON:0035825	92.85	gold quality
right adrenal gland	UBERON:0001233	92.56	gold quality
thyroid gland	UBERON:0002046	92.42	gold quality
left adrenal gland	UBERON:0001234	92.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.96	gold quality
adrenal cortex	UBERON:0001235	91.72	gold quality
right lobe of liver	UBERON:0001114	91.36	gold quality
metanephros cortex	UBERON:0010533	91.22	gold quality
apex of heart	UBERON:0002098	89.91	gold quality
mucosa of stomach	UBERON:0001199	89.11	gold quality
kidney epithelium	UBERON:0004819	89.08	gold quality
adrenal gland	UBERON:0002369	88.38	gold quality
spleen	UBERON:0002106	87.64	gold quality
minor salivary gland	UBERON:0001830	87.60	gold quality
gall bladder	UBERON:0002110	87.58	gold quality
rectum	UBERON:0001052	87.49	gold quality
small intestine Peyer’s patch	UBERON:0003454	86.81	gold quality
transverse colon	UBERON:0001157	86.61	gold quality
right hemisphere of cerebellum	UBERON:0014890	86.27	gold quality
sural nerve	UBERON:0015488	85.96	gold quality
monocyte	CL:0000576	85.71	gold quality
body of stomach	UBERON:0001161	85.66	gold quality
body of pancreas	UBERON:0001150	85.52	gold quality
upper lobe of left lung	UBERON:0008952	85.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00106 prevents against metastasis of thyroid cancer by inhibiting epithelial-mesenchymal transition. (PMID:33090406)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.