LINC00111

Summary

LINC00111 (long intergenic non-protein coding RNA 111, HGNC:1262) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1262
Approved symbol	LINC00111
Name	long intergenic non-protein coding RNA 111
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227702
Ensembl biotype	lncRNA
Entrez	54090
RNAcentral	URS000075D618 — lncRNA, 469 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000413718

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413718 — 3 exons

Exon	Start	End
ENSE00001672060	41679181	41679510
ENSE00001704971	41697238	41697336
ENSE00001747712	41688323	41688468

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 84.02.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
caudate nucleus	UBERON:0001873	84.02	gold quality
quadriceps femoris	UBERON:0001377	83.83	gold quality
cerebellar vermis	UBERON:0004720	82.87	gold quality
liver	UBERON:0002107	79.70	silver quality
skeletal muscle tissue	UBERON:0001134	77.85	silver quality
bone marrow	UBERON:0002371	77.55	silver quality
spleen	UBERON:0002106	71.81	silver quality
thymus	UBERON:0002370	70.94	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.66	gold quality
spinal cord	UBERON:0002240	68.35	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	61.08	gold quality
monocyte	CL:0000576	59.06	gold quality
lower esophagus mucosa	UBERON:0035834	56.09	gold quality
gall bladder	UBERON:0002110	54.59	gold quality
lower esophagus muscularis layer	UBERON:0035833	54.38	gold quality
sural nerve	UBERON:0015488	53.20	silver quality
esophagus	UBERON:0001043	52.71	gold quality
esophagus mucosa	UBERON:0002469	52.56	gold quality
small intestine	UBERON:0002108	52.42	gold quality
right uterine tube	UBERON:0001302	52.39	gold quality
prefrontal cortex	UBERON:0000451	51.43	gold quality
ectocervix	UBERON:0012249	50.83	gold quality
islet of Langerhans	UBERON:0000006	50.39	gold quality
kidney	UBERON:0002113	50.22	gold quality
gastrocnemius	UBERON:0001388	50.12	silver quality
frontal cortex	UBERON:0001870	49.91	gold quality
blood	UBERON:0000178	49.40	gold quality
urinary bladder	UBERON:0001255	49.10	gold quality
fallopian tube	UBERON:0003889	48.08	gold quality
stomach	UBERON:0000945	46.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.