LINC00159

Summary

LINC00159 (long intergenic non-protein coding RNA 159, HGNC:1285) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1285
Approved symbol	LINC00159
Name	long intergenic non-protein coding RNA 159
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230323
Ensembl biotype	lncRNA
Entrez	100551499
RNAcentral	URS000075B6E4 — lncRNA, 129 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000411605, ENST00000414877, ENST00000658887, ENST00000831887, ENST00000831888, ENST00000831889, ENST00000831890, ENST00000831891, ENST00000831892

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411605 — 5 exons

Exon	Start	End
ENSE00001749862	32083474	32083617
ENSE00004246924	32086204	32086298
ENSE00004246926	32080316	32080517
ENSE00004246932	32247221	32247266
ENSE00004246933	32245122	32245201

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 82.46.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.46	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.98	gold quality
sural nerve	UBERON:0015488	74.58	gold quality
ventricular zone	UBERON:0003053	68.65	gold quality
cortical plate	UBERON:0005343	68.30	gold quality
ganglionic eminence	UBERON:0004023	67.42	gold quality
right atrium auricular region	UBERON:0006631	62.52	gold quality
skeletal muscle tissue	UBERON:0001134	60.96	gold quality
calcaneal tendon	UBERON:0003701	60.74	gold quality
hindlimb stylopod muscle	UBERON:0004252	59.86	gold quality
bone marrow	UBERON:0002371	59.43	gold quality
monocyte	CL:0000576	59.26	gold quality
superior frontal gyrus	UBERON:0002661	58.47	gold quality
right testis	UBERON:0004534	58.14	gold quality
duodenum	UBERON:0002114	57.92	gold quality
prefrontal cortex	UBERON:0000451	57.21	gold quality
left testis	UBERON:0004533	56.97	gold quality
testis	UBERON:0000473	56.85	gold quality
placenta	UBERON:0001987	56.40	gold quality
heart	UBERON:0000948	55.68	gold quality
primary visual cortex	UBERON:0002436	55.44	gold quality
smooth muscle tissue	UBERON:0001135	54.66	gold quality
muscle of leg	UBERON:0001383	54.30	gold quality
gall bladder	UBERON:0002110	53.84	gold quality
nucleus accumbens	UBERON:0001882	53.50	gold quality
gastrocnemius	UBERON:0001388	53.34	gold quality
cerebellum	UBERON:0002037	53.18	gold quality
cerebellar cortex	UBERON:0002129	53.17	gold quality
cerebellar hemisphere	UBERON:0002245	53.00	gold quality
Ammon’s horn	UBERON:0001954	52.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.